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      Uso Terapéutico de la Amoxicilina-Ácido Clavulánico en la Enfermedad Periodontal

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          Abstract

          En el presente trabajo se estudia la combinación amoxicilina/ácido clavulánico como agente que puede ser utilizado en la terapia periodontal, basándose fundamentalmente en la revisión bibliográfica de comunicaciones científicas. Para ello se considera su efectividad clínica en las diferentes patologías periodontales, las pautas referentes a su indicación y administración, todo lo cual contribuirá a usarlo en una forma racional, con criterio equilibrado en la terapia de las periodontopatías.

          Translated abstract

          This review presents information about amoxicillin/clavulanic acid combination its clinical efficacy in the treatment of different periodontal pathologies, its dosage and application guidelines, to secure the best treatment on the basis of scientific knowledge.

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          Most cited references67

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          The significance of Candida albicans in denture stomatitis.

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            Antibiotic combinations: should they be tested?

            When antibiotic combinations are used to provide a broader spectrum of antimicrobial activity or in an attempt to prevent the emergence of resistant organisms, it is rarely necessary or practical to perform tests of drug interactions in vitro. In vitro testing of combinations may be useful when combinations are used in an attempt to attain synergistic interactions. In some cases, screening methods can be used as substitutes for formal synergy testing. This paper examines the mechanisms of antibiotic interaction leading to synergism or antagonism, surveys attempts to correlate in vitro observations with efficacy in animal models, and reviews clinical data providing evidence for or against a useful role of synergistic antibiotic interactions in the treatment of human infections.
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              Chemotherapy of dental plaque infections.

              W Loesche (1975)
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                Author and article information

                Contributors
                Role: ND
                Journal
                aov
                Acta Odontológica Venezolana
                Acta odontol. venez
                Facultad de Odontología -UCV (Caracas )
                0001-6365
                December 2002
                : 40
                : 3
                : 320-328
                Affiliations
                [1 ] Universidad Central de Venezuela
                Article
                S0001-63652002000300015
                d2d0b5ff-19ce-4998-bbc0-e3db3cbef0d4

                http://creativecommons.org/licenses/by/4.0/

                History
                Product

                SciELO Venezuela

                Self URI (journal page): http://www.scielo.org.ve/scielo.php?script=sci_serial&pid=0001-6365&lng=en
                Categories
                DENTISTRY, ORAL SURGERY & MEDICINE

                Dentistry
                Amoxicillin/clavulanic acid,periodontal disease,periodontal therapy,Amoxicilina/ácido clavulánico,enfermedad periodontal,terapia periodontal

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