Long-term citrate anticoagulation for high-flux haemodialysis in a patient with heparin-induced thrombocytopenia type II.

Abstract

For the first time, long-term use of regional citrate anticoagulation for high-flux haemodialysis is reported in a patient with heparin-induced thrombocytopenia type II. A simple, flow-independent, citrate infusion protocol allowed efficient anticoagulation. Excellent solute removal, indicated by KT/V values of 1.52 to 1.98, was achieved. Electrolyte and acid-base balance as well as calcium homeostasis were well controlled over a period of 9 months.