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      Hypoglycemia in Infants and Effect on Neurodevelopment

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      Author(s): , MD 1 , 2 , , MD, PhD 1 , 2 , *
      Publication date (Electronic, pub):
      Publication date (Electronic, collection):
      Journal: Pediatric Neurology Briefs
      Publisher: Pediatric Neurology Briefs Publishers
      Keywords: Hypoglycemia, Child Development, Blood Glucose, Infant, Newborn

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          Abstract

          In a prospective, randomized treatment trial, investigators from multiple institutions in the HypoEXIT Study Group investigated the developmental outcomes after neonatal hypoglycemia, comparing the traditional glucose threshold 47 mg/dL vs. 36 mg/dL.

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          Postnatal glucose homeostasis in late-preterm and term infants.

          , David Adamkin (2011)
          This report provides a practical guide and algorithm for the screening and subsequent management of neonatal hypoglycemia. Current evidence does not support a specific concentration of glucose that can discriminate normal from abnormal or can potentially result in acute or chronic irreversible neurologic damage. Early identification of the at-risk infant and institution of prophylactic measures to prevent neonatal hypoglycemia are recommended as a pragmatic approach despite the absence of a consistent definition of hypoglycemia in the literature.
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            Association of Neonatal Glycemia With Neurodevelopmental Outcomes at 4.5 Years

            Christopher McKinlay, Jane Alsweiler, Nicola Anstice … (2017)
            Hypoglycemia is common during neonatal transition and may cause permanent neurological impairment, but optimal intervention thresholds are unknown.
            Article 0 comments Cited 102 times – based on 0 reviews     Review now
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              Neonatal Glycemia and Neurodevelopmental Outcomes at 2 Years.

              Christopher McKinlay, Jane Alsweiler, Judith Ansell … (2015)
              Neonatal hypoglycemia is common and can cause neurologic impairment, but evidence supporting thresholds for intervention is limited.
              Article 0 comments Cited 93 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): Pediatr Neurol Briefs
                Journal ID (iso-abbrev): Pediatr Neurol Briefs
                Journal ID (issn): 1043-3155
                Journal ID (pmc): pedneurbriefs
                Journal ID (publisher-id): Pediatr Neurol Briefs
                Title: Pediatric Neurology Briefs
                Publisher: Pediatric Neurology Briefs Publishers (Chicago, IL, USA )
                ISSN (Print): 1043-3155
                ISSN (Electronic): 2166-6482
                Publication date (Electronic, pub): 18 December 2020
                Publication date (Electronic, collection): 2020
                Volume: 34
                Page: 18
                Affiliations
                [1 ]Division of Neurology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
                [2 ]Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL
                Author notes
                [* ]Correspondence: Dr. Tracy S. Gertler, E-mail: tgertler@ 123456luriechildrens.org
                Article
                Publisher ID: PNB-34-18
                DOI: 10.15844/pedneurbriefs-34-18
                PMC ID: 7747512
                SO-VID: d5001195-3000-4b63-81dd-f4eae888eb8b
                Copyright © Copyright: © 2020 The Author(s)
                License:

                This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 20 March 2020
                Date accepted : 05 December 2020
                Related
                Lower versus Traditional Treatment Threshold for Neonatal Hypoglycemia
                Categories
                Subject: Neonatal Disorders
                Subject: Neurology
                Subject: Pediatrics
                Subject: Nervous System Diseases
                Subject: Child Development
                Subject: Brain Diseases
                Subject: Neurosurgery
                Subject: Child
                Subject: Infant

                Keywords: hypoglycemia,child development,blood glucose,infant,newborn
                Data availability:
                Keywords: hypoglycemia, child development, blood glucose, infant, newborn

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