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      Simvastatin promotes osteogenic differentiation of mesenchymal stem cells in rat model of osteoporosis through BMP-2/Smads signaling pathway.

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          Abstract

          By establishing osteoporosis (OP) model in rats, the specific regulatory effect of simvastatin on promoting the differentiation of mesenchymal stem cells (MSCs) into osteoblasts through the bone morphogenetic protein 2 (BMP-2)/Smads signaling pathway was investigated.

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          Author and article information

          Journal
          Eur Rev Med Pharmacol Sci
          European review for medical and pharmacological sciences
          2284-0729
          1128-3602
          January 2020
          : 24
          : 1
          Affiliations
          [1 ] Department of Orthopedics, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, China. zjgzyyxl@163.com.
          Article
          10.26355/eurrev_202001_19943
          31957858
          d65cb558-cbb5-4b43-bede-420bff422d90
          History

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