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      Graphene-based nanomaterials for drug delivery and tissue engineering.

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          Abstract

          Nanomaterials offer interesting physicochemical and biological properties for biomedical applications due to their small size, large surface area and ability to interface/interact with the cells/tissues. Graphene-based nanomaterials are fast emerging as "two-dimensional wonder materials" due to their unique structure and excellent mechanical, optical and electrical properties and have been exploited in electronics and other fields. Emerging trends show that their exceptional properties can be exploited for biomedical applications, especially in drug delivery and tissue engineering. This article presents a comprehensive review of various types and properties of graphene family nanomaterials. We further highlight how these properties are being exploited for drug delivery and tissue engineering applications.

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          Author and article information

          Journal
          J Control Release
          Journal of controlled release : official journal of the Controlled Release Society
          1873-4995
          0168-3659
          Jan 10 2014
          : 173
          Affiliations
          [1 ] Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh 15261, USA.
          [2 ] Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh 15261, USA; Department of Bioengineering, Pittsburgh 15261, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh 15219, USA. Electronic address: shs149@pitt.edu.
          Article
          S0168-3659(13)00847-X
          10.1016/j.jconrel.2013.10.017
          24161530
          d66709be-48b4-4bb0-89e1-922a94f06ec7
          © 2013.
          History

          Cell–material interactions,Drug delivery,Graphene nanomaterials,Tissue engineering

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