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      Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment.

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          Abstract

          To evaluate the total number of synapses in the stratum radiatum (str rad) of the human hippocampal CA1 subfield in individuals with mild Alzheimer disease (mAD), mild cognitive impairment (MCI), or no cognitive impairment (NCI) and determine if synapse loss is an early event in the progression of the disease.

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          Author and article information

          Journal
          Neurology
          Neurology
          Ovid Technologies (Wolters Kluwer Health)
          1526-632X
          0028-3878
          May 01 2007
          : 68
          : 18
          Affiliations
          [1 ] Sanders-Brown Center on Aging and Alzheimer Disease Research Center, University of Kentucky College of Medicine, Lexington, KY 40536-0230, USA. sscheff@email.uky.edu
          Article
          68/18/1501
          10.1212/01.wnl.0000260698.46517.8f
          17470753
          d6ef6f07-2f8e-44a2-ab3a-12fae777c20a
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