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      Ticagrelor Pharmacokinetics and Pharmacodynamics in Chinese Patients with STEMI and NSTEMI Without Opioid Administration.

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          Abstract

          The pharmacodynamics (PD) and pharmacokinetics (PK) study of ticagrelor loading dose (LD) in Chinese patients with acute coronary syndrome (ACS) without opioid administration has never been investigated. Therefore, the aim of this study was to evaluate the antiplatelet effects and the PK parameters of ticagrelor in Chinese patients with ACS without opioid administration.

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          Author and article information

          Journal
          Adv Ther
          Advances in therapy
          Springer Science and Business Media LLC
          1865-8652
          0741-238X
          October 2020
          : 37
          : 10
          Affiliations
          [1 ] Department of Cardiology, Zhongshan Hospital, Fudan University. Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
          [2 ] Department of Cardiology, Xiamen Branch, Zhongshan Hospital, Fudan University, Xiamen, Fujian Province, China.
          [3 ] Department of Cardiology, Zhongshan Hospital, Fudan University. Shanghai Institute of Cardiovascular Diseases, Shanghai, China. qian.juying@zs-hospital.sh.cn.
          Article
          10.1007/s12325-020-01423-w
          10.1007/s12325-020-01423-w
          32770531
          d77d780f-4c4b-4529-85f2-423a22f8563e
          History

          Acute coronary syndrome,Antiplatelet effect,Pharmacokinetics,Ticagrelor

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