Effects of enamel matrix proteins in combination with a bovine-derived natural bone mineral for the repair of bone defects.

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Abstract

Previously, the use of enamel matrix derivative (EMD) in combination with a natural bone mineral (NBM) was able to stimulate periodontal ligament cell and osteoblast proliferation and differentiation. Despite widespread use of EMD for periodontal applications, the effects of EMD on bone regeneration are not well understood. The aim of the present study was to test the ability of EMD on bone regeneration in a rat femur defect model in combination with NBM.

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Author and article information

Journal

Journal ID (iso-abbrev): Clin Oral Investig

Title: Clinical oral investigations

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1436-3771

ISSN (Print): 1432-6981

Publication date (Electronic): 2014

Volume: 18

Issue: 2

Affiliations

[1 ] The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, 237 Luoyu Road, Wuhan, 430079, People's Republic of China.

Article

DOI: 10.1007/s00784-013-0992-5

PubMed ID: 23652357

SO-VID: dab482a9-6393-4c39-a9d1-8837dd2eba7b

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