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Association study between polymorphisms in the CACNA1A, CACNA1C, and CACNA1H genes and drug-resistant epilepsy in the Chinese Han population
August 2015
August 2015
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Abstract
As important ion channels of the central nervous system, calcium channels not only
take part in epileptogenesis but also act as the targets of commonly used antiepileptic
drugs (AEDs). Thus, this study aimed to provide the first investigation of the association
between CACNA1A, CACNA1C, and CACNA1H single nucleotide polymorphisms (SNPs) and AED
resistance in the Chinese Han population.