Endovascular therapy for acute ischaemic stroke: a systematic review and meta-analysis of randomized trials.

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Abstract

Evidence from randomized controlled trials (RCTs) evaluating possible benefits of endovascular therapy (EVT) for acute ischaemic stroke has shown conflicting results. The purpose of this meta-analysis was to systematically examine clinical outcomes in RCTs comparing the use of intravenous (IV) fibrinolysis alone to IV fibrinolysis plus EVT, for the treatment of acute ischaemic stroke.

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Author and article information

Journal

Journal ID (iso-abbrev): Eur. Heart J.

Title: European heart journal

ISSN (Electronic): 1522-9645

ISSN (Print): 0195-668X

Publication date (Electronic): Sep 14 2015

Volume: 36

Issue: 35

Affiliations

[1 ] Division of Cardiovascular Medicine, University of Utah Health Science Center, University of Utah, 30 North 1900 East, Salt Lake City, UT 84132, USA parthasardarmd@gmail.com.

[2 ] St Luke's-Roosevelt Hospital of the Mount Sinai Health System, New York, NY, USA.

[3 ] Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

[4 ] University of Massachusetts Medical School, Worcester, MA, USA.

[5 ] Division of Cardiovascular Medicine, University of Utah Health Science Center, University of Utah, 30 North 1900 East, Salt Lake City, UT 84132, USA.

[6 ] Saint Michael's Medical Center, Newark, NJ, USA.

[7 ] University of Arkansas for Medical Sciences, Little Rock, AR, USA.

[8 ] Temple University School of Medicine, Philadelphia, PA, USA.

[9 ] University Hospitals Case Medical Center, Cleveland, OH, USA.

[10 ] Ochsner Clinical School, Ochsner Medical Center, New Orleans, LA, USA.

[11 ] Radiology and Neurological Surgery, Columbia University Medical Center, New York, NY, USA.

[12 ] Texas Tech University Health Sciences Center, El Paso, TX, USA.

[13 ] Division of Vascular Neurology, University of Utah, Salt Lake City, UT, USA.

[14 ] Center for Interventional Vascular Therapy, Columbia University Medical Center, New York, NY, USA.

Article

Publisher Item ID: ehv270

DOI: 10.1093/eurheartj/ehv270

PubMed ID: 26071599

SO-VID: e4b20c26-6700-4329-89f2-df243462c11e

History

Keywords: Endovascular,Meta-analysis,Outcomes,Stroke,Thrombolytics

Data availability:

Keywords: Endovascular, Meta-analysis, Outcomes, Stroke, Thrombolytics

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