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High level PSMA expression is associated with early PSA recurrence in surgically treated prostate cancer.
Sarah Minner
1 ,
Corinna Wittmer ,
Markus Graefen ,
Georg Salomon ,
Thomas Steuber ,
Alexander Haese ,
Hartwig Huland ,
Carsten Bokemeyer ,
Emre Yekebas ,
Judith Dierlamm ,
Stefan Balabanov ,
Ergin Kilic ,
Waldemar Wilczak ,
Ronald Simon ,
Guido Sauter ,
Thorsten Schlomm
Feb 15 2011
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Abstract
Prostate specific membrane antigen (PSMA) is a suggested target for antibody-based therapy of prostate cancer potentially involved in the regulation of cell migration. This study was undertaken, to gain more insight on the role of PSMA in early prostate cancer and its distribution in various normal tissues.