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      Sleep deprivation in healthy elderly men and women: effects on mood and on sleep during recovery.

      Sleep
      Aged, Analysis of Variance, Female, Humans, Male, Mood Disorders, etiology, Myoclonus, physiopathology, Sleep, physiology, Sleep Apnea Syndromes, Sleep Deprivation, Sleep Disorders, Sleep, REM

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          Abstract

          Elderly women had better recovery sleep than elderly men following 36-h sleep deprivation, as evidenced by higher sleep maintenance/efficiency and more slow wave sleep (particularly in the amount of stage 4 sleep). During recovery sleep, both groups showed REM latency reduction (two men and three women had seven sleep-onset REM periods out of a total of 40 recovery nights), decrease in percentage of early REM sleep and increase in whole-night REM sleep time. Total Mood Disturbance scores on the Profile of Mood States increased in both men and women following sleep deprivation (reflecting a decrease in vigor and increase in fatigue and tension). While the increase tended to be greater in women, in both groups self-ratings of mood returned to baseline after 1 night of recovery sleep. These observations underscore the importance of gender in determining late-life sleep structure and suggest that the ability of older women to achieve slow wave sleep and to have long uninterrupted sleep in greater than that of men.

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