Endogenous Toll-like Receptor 2 Modulates Th1/Treg-Promoting Dendritic Cells in Mice Corneal Transplantation Model.

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Abstract

Endogenous toll-like receptor (TLR) 2 is linked to allograft rejection in corneal transplantation. TLR2 also could modulate dendritic cell (DC) phenotype, resulting in T cell polarization. Thus, we investigated the role of endogenous TLR2 on DC development and T cell polarization during corneal rejection.

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Journal

Journal ID (iso-abbrev): Curr Eye Res

Title: Current eye research

Publisher: Informa UK Limited

ISSN (Electronic): 1460-2202

ISSN (Print): 0271-3683

Publication date (Electronic): July 2020

Volume: 45

Issue: 7

Affiliations

[1 ] Department of ophthalmology, Nanfang Hospital, Southern Medical University , Guangzhou, China.

[2 ] State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University , Guangzhou, China.

Article

DOI: 10.1080/02713683.2019.1705491

PubMed ID: 31842628

SO-VID: e7163aea-38d3-4da8-818d-66353c64fcfe

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Keywords: Toll-like receptor 2,dendritic cell,cornea,allograft; rejection

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Keywords: Toll-like receptor 2, dendritic cell, cornea, allograft; rejection

Endogenous Toll-like Receptor 2 Modulates Th1/Treg-Promoting Dendritic Cells in Mice Corneal Transplantation Model.

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Gamma Delta T cells

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