Syndrome of Inappropriate Secretion of Antidiuretic Hormone due to Malignant Thymoma

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Abstract

The authors present the case of a 51-year-old female with a syndrome of inappropriate secretion of antidiuretic hormone (SIADH) due to a malignant thymoma. Laboratory examinations of the patient showed hyponatremia, plasma hypoosmolarity in the presence of concentrated urine and normal urine excretion of sodium. CT revealed a mass lesion in the mediastinum. A biopsy of the mediastinal mass was performed and the diagnosis of thymoma with SIADH was established. This is a rare description of a malignant thymoma associated with SIADH.

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Journal ID (publisher-id): NEF

Journal ID (nlm-ta): Nephron

Journal ID (doi): 10.1159/issn.1660-8151

Title: Nephron

Publisher: S. Karger AG

ISSN (Print): 1660-8151

ISSN (Electronic): 2235-3186

Publication date Subscription-year: 2002

Publication date (Print): August 2002

Publication date (Electronic): 15 July 2002

Volume: 91

Issue: 4

Pages: 752-754

Affiliations

Departments of ^aMedicine and ^bPathology, Dubrava University Hospital, Zagreb, and ^cDepartment of Medicine, S. Milosrdnice University Hospital, Zagreb, Croatia

Article

Publisher ID: 65042 Other ID: Nephron 2002;91:752–754

DOI: 10.1159/000065042

PubMed ID: 12138284

SO-VID: ec1678bd-8aca-49de-8610-56bacb890ca6

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Syndrome of Inappropriate Secretion of Antidiuretic Hormone due to Malignant Thymoma

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Karger: Nephrology

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