Effect of Vericiguat, a Soluble Guanylate Cyclase Stimulator, on Natriuretic Peptide Levels in Patients With Worsening Chronic Heart Failure and Reduced Ejection Fraction: The SOCRATES-REDUCED Randomized Trial.

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Abstract

Worsening chronic heart failure (HF) is a major public health problem.

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Journal

Journal ID (iso-abbrev): JAMA

Title: JAMA

ISSN (Electronic): 1538-3598

ISSN (Print): 0098-7484

Publication date (Electronic): Dec 1 2015

Volume: 314

Issue: 21

Affiliations

[1 ] Center for Cardiovascular Innovation, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

[2 ] Division of Cardiology, Duke University Medical Center, Durham, North Carolina.

[3 ] Division of Cardiology, Stony Brook University, Stony Brook, New York.

[4 ] Heart Failure Unit, Department of Cardiology, Athens University Hospital Attikon, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

[5 ] Department of Cardiology, National Heart Centre Singapore and Duke, National University of Singapore, Singapore.

[6 ] Associazione Nazionale Medici Cardiologi Ospedalieri Research Center, Florence, Italy.

[7 ] Department of Heart Diseases, Medical University, Military Hospital, Wroclaw, Poland.

[8 ] Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

[9 ] Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts.

[10 ] Department of Internal Medicine and Cardiology, Charité University Medicine Berlin-Campus Virchow Klinikum, Berlin, Germany.

[11 ] Bayer, São Paulo, Brazil.

[12 ] Bayer Pharma, Wuppertal, Germany.

[13 ] Department of Internal Medicine and Cardiology, Charité University Medicine Berlin-Campus Virchow Klinikum, Berlin, Germany13Department of Internal Medicine and Cardiology, German Heart Center Berlin, Berlin, Germany.

Article

Publisher Item ID: 2469195

DOI: 10.1001/jama.2015.15734

PubMed ID: 26547357

SO-VID: edf07609-6019-4688-a756-5d405c9c3969

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