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      The prognostic role of the epithelial-mesenchymal transition markers E-cadherin and Slug in laryngeal squamous cell carcinoma.

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          Abstract

          Laryngeal squamous cell carcinoma (LSCC) prognosis is definitely related to lymph node metastasis. Epithelial-mesenchymal transition (EMT) allows neoplastic cells to gain the plasticity and motility required for tumour progression and metastasis. The aim of this study was to investigate the role of EMT in the prognosis of LSCC.

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          Author and article information

          Journal
          Histopathology
          Histopathology
          1365-2559
          0309-0167
          Oct 2015
          : 67
          : 4
          Affiliations
          [1 ] Surgical Pathology and Cytopathology Unit, Department of Medicine, University of Padova, Padova, Italy.
          [2 ] Otolaryngology Section, Department of Neurosciences, University of Padova, Padova, Italy.
          [3 ] Radiotherapy Unit, Istituto Oncologico Veneto IOV, IRCCS, Padova, Italy.
          Article
          10.1111/his.12668
          25684546
          ef8a3d92-17eb-4f89-9727-b9a64a503215
          © 2015 John Wiley & Sons Ltd.
          History

          epithelial-mesenchymal transition,laryngeal carcinoma,neck lymph node metastasis,prognosis

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