Contributors
Kun Miao: Role: Data curationRole: Formal analysisRole: Funding acquisitionRole: InvestigationRole:
MethodologyRole: Project administrationRole: SoftwareRole: Writing – original draft
Ling Zhou: Role: Data curationRole: Formal analysisRole: Funding acquisitionRole: InvestigationRole:
MethodologyRole: Project administrationRole: Software
Hongping Ba: Role: MethodologyRole: Project administrationRole: ValidationRole: Visualization
Chenxi Li: Role: MethodologyRole: Project administration
Haiyan Gu: Role: MethodologyRole: Project administration
Bingjiao Yin: Role: Supervision
Jing Wang: Role: Supervision
Xiang-ping Yang: Role: Writing – review & editing
Zhuoya Li: Role: ConceptualizationRole: Funding acquisitionRole: InvestigationRole: SupervisionRole:
VisualizationRole: Writing – review & editing
Dao Wen Wang:
ORCID: https://orcid.org/0000-0002-9774-3980
Role: ConceptualizationRole: Funding acquisitionRole: InvestigationRole: ResourcesRole:
SupervisionRole: VisualizationRole: Writing – review & editing
Cecilia W. Lo: Role: Academic Editor
Journal
Journal ID (nlm-ta): PLoS Biol
Journal ID (iso-abbrev): PLoS Biol
Journal ID (publisher-id): plos
Journal ID (pmc): plosbiol
Title:
PLoS Biology
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1544-9173
ISSN
(Electronic):
1545-7885
Publication date
(Electronic):
3
December
2020
Publication date Collection:
December
2020
Publication date PMC-release: 3
December
2020
Volume: 18
Issue: 12
Electronic Location Identifier: e3000967
Affiliations
[1
]
Division of Cardiology, Department of Internal Medicine and Department of Hubei Key
Laboratory of Genetics and Molecular Mechanisms of Cardiologic Disorders, Tongji Hospital,
Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei,
China
[2
]
Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong
University of Science and Technology, Wuhan, Hubei, China
University of Pittsburgh, UNITED STATES
Author notes
The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PBIOLOGY-D-19-02339
DOI: 10.1371/journal.pbio.3000967
PMC ID: 7714153
PubMed ID: 33270628
SO-VID: f05d14fd-57cc-49c8-8748-70863df59f66
Copyright © © 2020 Miao et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 10
August
2019
Date
accepted
: 23
October
2020
Page count
Figures: 8,
Tables: 0,
Pages: 25
Funding
Funded by: funder-id http://dx.doi.org/10.13039/501100001809, National Natural Science Foundation of China;
Award ID: 81471899
Award Recipient
:
Zhuoya Li
Funded by: funder-id http://dx.doi.org/10.13039/501100001809, National Natural Science Foundation of China;
Award ID: 3167080495
Award Recipient
:
Zhuoya Li
Funded by: funder-id http://dx.doi.org/10.13039/501100001809, National Natural Science Foundation of China;
Award ID: 81800335
Award Recipient
:
Kun Miao
Funded by: funder-id http://dx.doi.org/10.13039/501100001809, National Natural Science Foundation of China;
Award ID: 81800355
Award Recipient
:
Ling Zhou
Funded by: funder-id http://dx.doi.org/10.13039/501100012226, Fundamental Research Funds for the Central Universities;
Award ID: No. 2015ZDTD044
Award Recipient
:
ORCID: https://orcid.org/0000-0002-9774-3980
Dao Wen Wang
This study was supported by the General Program of National Natural Science Foundation
of China (81471899 and 3167080495) (to ZL), Youth Program of National Natural Science
Foundation of China (81800335) (to KM), Youth Program of National Natural Science
Foundation of China (81800355) (to LZ), and Fundamental Research Funds for the Central
Universities (2015ZDTD044) (to DWW). The funders had no role in study design, data
collection and analysis, decision to publish, or preparation of the manuscript.
Categories
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Cytokines
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System
Subject:
Innate Immune System
Subject:
Cytokines
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune System
Subject:
Innate Immune System
Subject:
Cytokines
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Molecular Development
Subject:
Cytokines
Subject:
Medicine and Health Sciences
Subject:
Cardiology
Subject:
Cardiac Hypertrophy
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Muscle Cells
Subject:
Cardiomyocytes
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Muscle Tissue
Subject:
Muscle Cells
Subject:
Cardiomyocytes
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Muscle Tissue
Subject:
Muscle Cells
Subject:
Cardiomyocytes
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
Gene regulation
Subject:
Small interfering RNA
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
RNA
Subject:
Non-coding RNA
Subject:
Small interfering RNA
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Heart
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Heart
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cell Processes
Subject:
Cell Death
Subject:
Apoptosis
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Hormones
Subject:
Peptide Hormones
Subject:
Natriuretic Peptide
Subject:
Atrial Natriuretic Peptide
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Hormones
Subject:
Peptide Hormones
Subject:
Natriuretic Peptide
Subject:
Brain Natriuretic Peptide
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