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Point-of-care thromboelastography/thromboelastometry-based coagulation management in cardiac surgery: a meta-analysis of 8332 patients.
Antje-Christin Deppe
1 ,
Carolyn Weber
2 ,
Julia Zimmermann
2 ,
Elmar W Kuhn
2 ,
Ingo Slottosch
2 ,
Oliver J Liakopoulos
2 ,
Yeong-Hoon Choi
3 ,
Thorsten Wahlers
2
Jun 15 2016
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Abstract
Severe bleeding related to cardiac surgery is associated with increased morbidity and mortality. Thromboelastography (TEG) and thromboelastometry (ROTEM) are point-of-care tests (POCT). Bedside ROTEM/TEG can rapidly detect changes in blood coagulation and therefore provide a goal-directed, individualized coagulation therapy. In this meta-analysis, we aimed to determine the current evidence for or against POCT-guided algorithm in patients with severe bleeding after cardiac surgery.