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      Is Open Access

      Self-Reported Health Complaints in Women Undergoing Explantation of Breast Implants

      research-article
      , MD, , MD, PhD
      Aesthetic Surgery Journal
      Oxford University Press

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          Abstract

          Background

          Concerns about the safety of silicone breast implants (SBIs) have existed for years, but a causal relation between systemic complaints and SBIs has not been proven. Nevertheless, some women are worried and even request explantation.

          Objectives

          This study aimed to review the explantation procedures performed, focusing on patient-reported symptoms preoperatively, the effect of explantation, and the effect of breast reconstruction on these symptoms.

          Methods

          A retrospective chart review was performed for patients who had undergone explantation between 2010 and 2020 at Maastricht University Medical Center. Patients who had undergone tissue expander removal, tissue expander–implant exchange, or direct implant exchange were excluded.

          Results

          More than half of the patients undergoing explantation reported complaints, mostly pain. Some 15% reported systemic complaints they believed were implant related. Breast implant illness (BII) was found to be the fifth most common indication for explantation (11.2%). A history of either allergies or implant rupture resulted in higher odds ratios of having BII (odd ratios, 2.1 and 2.1, respectively). Subjective improvement of BII after explantation was reported by about 60% of patients.

          Conclusions

          A relatively low prevalence of suggested BII exists among women undergoing explantation; 1 in 9 procedures were performed for this reason. Allergy and implant rupture may increase the likelihood of having BII. About 60% of BII patients experienced an improvement in their complaints after implant removal. Autologous breast reconstruction appears a good alternative. Prospective studies into health complaints and quality of life should be performed to confirm the effectiveness of explantation as a therapy for BII.

          Level of Evidence: 4

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          Most cited references35

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          'ASIA' - autoimmune/inflammatory syndrome induced by adjuvants.

          The role of various environmental factors in the pathogenesis of immune mediated diseases is well established. Of which, factors entailing an immune adjuvant activity such as infectious agents, silicone, aluminium salts and others were associated with defined and non-defined immune mediated diseases both in animal models and in humans. In recent years, four conditions: siliconosis, the Gulf war syndrome (GWS), the macrophagic myofasciitis syndrome (MMF) and post-vaccination phenomena were linked with previous exposure to an adjuvant. Furthermore, these four diseases share a similar complex of signs and symptoms which further support a common denominator.Thus, we review herein the current data regarding the role of adjuvants in the pathogenesis of immune mediated diseases as well as the amassed data regarding each of these four conditions. Relating to the current knowledge we would like to suggest to include these comparable conditions under a common syndrome entitled ASIA, "Autoimmune (Auto-inflammatory) Syndrome Induced by Adjuvants". Copyright © 2010 Elsevier Ltd. All rights reserved.
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            US FDA Breast Implant Postapproval Studies

            To analyze the long-term safety and efficacy outcomes of patients with breast implants.
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              Features of somatization predict the onset of chronic widespread pain: results of a large population-based study.

              Chronic widespread pain, the clinical hallmark of the fibromyalgia syndrome, is associated with other physical and psychological symptoms both in patients studied in a clinical setting and in those identified in the community. The present study was undertaken to examine the hypothesis that psychological and physical indicators of the process of somatization predict the development of new chronic widespread pain. In this population-based prospective study, 1,658 adults ages 18-65 years completed a detailed pain questionnaire, which included a pain drawing. They also completed the following psychosocial instruments: General Health Questionnaire, Somatic Symptom Checklist, Fatigue Questionnaire, and Illness Attitude Scales. Individuals were followed up at 12 months, at which time 1,480 (93% of subjects still living at their baseline address) provided data on pain status, using the same instruments. At baseline, 825 subjects were classified as pain free and 833 as having pain not satisfying criteria for chronic widespread pain. Of those, 18 (2%) and 63 (8%), respectively, were classified as having chronic widespread pain at followup. After adjustment for age and sex, there were strong relationships between baseline test scores and subsequent risk of chronic widespread pain (odds ratio for the Somatic Symptom Checklist 3.3; odds ratio for the Illness Behavior subscale of the Illness Attitude Scales 9.0). All 95% confidence intervals excluded unity. These associations were independent of baseline pain status. Subjects who are free of chronic widespread pain are at increased future risk of its development if they display other aspects of the process of somatization. Data from this population-based prospective study lend powerful support to the hypothesis that chronic widespread pain can be one manifestation of the somatization of distress.
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                Author and article information

                Journal
                Aesthet Surg J
                Aesthet Surg J
                asj
                Aesthetic Surgery Journal
                Oxford University Press (US )
                1090-820X
                1527-330X
                February 2022
                30 November 2020
                30 November 2020
                : 42
                : 2
                : 171-180
                Affiliations
                From the Department of Plastic, Reconstructive and Hand Surgery, Maastricht University Medical Center , Maastricht, The Netherlands
                Author notes
                Corresponding Author: Dr Renée M.L. Miseré, Department of Plastic and Reconstructive Surgery, P. Debyelaan 25, 6229 HX Maastricht, The Netherlands. E-mail: renee.misere@ 123456mumc.nl
                Author information
                https://orcid.org/0000-0001-5511-2294
                Article
                sjaa337
                10.1093/asj/sjaa337
                8756082
                33252630
                f2de805c-afb9-4987-9bd1-d2fa2f7d78b5
                © 2020 The Aesthetic Society.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

                History
                : 24 November 2020
                : 23 January 2021
                Page count
                Pages: 9
                Categories
                Breast Surgery
                Original Article
                Asj/2
                AcademicSubjects/MED00987

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