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      Human Immunodeficiency Virus-Associated Kaposi’s Sarcoma in a Pediatric Renal Transplant Recipient

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          Abstract

          An 11-year-old boy developed Kaposi’s sarcoma and progressive T lymphocyte deficiency 5 years after cadaveric kidney transplantation for end-stage renal disease. He had received 17 individual red blood cell transfusions prior to and during transplantation in 1980. Human immunodeficiency virus (HIV) was cultured from blood in cerebrospinal fluid and HIV antibodies were detected with enzyme immunoassay and immunoblot techniques. The recipient of the donor’s other kidney was well and HIV antibody-negative. The patient was treated with etoposide with excellent although transient regression of tumor. Allograft function has remained stable despite minimal immunosuppressive therapy and the need for high-dose anticonvulsant therapy. This case represents the first pediatric patient with acquired immune deficiency syndrome (AIDS) and Kaposi’s sarcoma following kidney transplantation.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1987
          1987
          05 December 2008
          : 47
          : 1
          : 62-65
          Affiliations
          aO1ive View Medical Center, Sylmar, Calif., and Divisions of bAllergy and Immunology, cHematology/Oncology, dNeurology and eNephrology, Childrens Hospital of Los Angeles, University of Southern California School of Medicine, Los Angeles, Calif., USA
          Article
          184458 Nephron 1987;47:62–65
          10.1159/000184458
          3306430
          © 1987 S. Karger AG, Basel

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          Page count
          Pages: 4
          Categories
          Original Paper

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