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      Indocyanine Green Assisted Removal of Orbital Lacrimal Duct Cysts in Children

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          Abstract

          Aim. To report on the use of indocyanine green (ICG) during surgical removal of pediatric orbital lacrimal duct cysts. Method. We conducted a retrospective review of our cases of surgical excision of orbital lacrimal duct cysts using intraoperative injection of indocyanine green (ICG), which was used following inadvertent cyst rupture and volume loss. The dye allowed complete cyst visualization and complete excision despite volume loss or cyst rupture. Results. The study included 6 children (3 boys, mean age of 4.2 ± 0.84 years, range 3–5 years). Mean follow-up period was 9.3 months. All cysts were located in the inferonasal quadrant of the orbit (4 in the right side). In all cases, ICG was injected into the cyst at the time of surgery following unintentional cyst rupture. After the dye injection, it was easy to identify the borders of the cyst, permitting complete cyst removal, without any intra- or postoperative complications. Pathological examination revealed that all cysts were of lacrimal duct origin. Conclusion. Intraoperative injection of ICG into orbital cysts in children can aid surgeons in identifying cyst borders following inadvertent rupture, allowing complete removal.

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          Most cited references14

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          The use of vital dyes in ocular surgery.

          Vital dyes have advanced diagnosis and surgical technique in various specialties, including oncology, gastroenterology, and ophthalmology. In ocular surgery vital dyes are widely used in cataract and vitreoretinal surgery. Worldwide, intra-operative use of trypan blue during cataract surgery has enhanced visualization of the anterior capsule during capsulorrhexis, and patent blue has been recently licensed in Europe for cataract surgery. For chromovitrectomy, the vital dyes indocyanine green, infracyanine green, and brilliant blue stain the internal limiting membrane, and trypan blue and triamcinolone acetonide help visualize epiretinal membranes and vitreous, respectively. Intra-operative vital dyes are finding uses in corneal, glaucoma, orbit, strabismus, and conjunctival surgery. We provide a summary of current knowledge of the use of vital dyes in ocular surgery. We review the properties of dyes, techniques of application, indications, and complications in ocular surgery. Vital dyes represent an expanding area of research, and novel dyes deserve further investigation.
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            Lacrimal Sac Tumors

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              Lacrimal ductal cysts.

              Cyst formation can occur in any location where lacrimal gland tissue is present. A new classification is proposed based on these locations: palpebral lobe cysts (simple dacryops); orbital lobe cysts; cysts of the accessory lacrimal glands of Krause and Wolfring; and cysts of ectopic (choristomatous) lacrimal glands. The characteristic clinical presentation, histopathology, and treatment of these lacrimal ductal cysts is described.
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                Author and article information

                Journal
                J Ophthalmol
                J Ophthalmol
                JOPH
                Journal of Ophthalmology
                Hindawi Publishing Corporation
                2090-004X
                2090-0058
                2015
                8 January 2015
                : 2015
                : 130215
                Affiliations
                1Oculoplastic and Orbital Institute and Department of Ophthalmology, Tel Aviv Medical Center, 64239 Tel Aviv, Israel
                2The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
                3Department of Neonatology, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel
                4South Australian Institute of Ophthalmology, Royal Adelaide Hospital, University of Adelaide, Adelaide, SA, Australia
                Author notes

                Academic Editor: Enrico Peiretti

                Author information
                http://orcid.org/0000-0002-1187-2467
                http://orcid.org/0000-0002-2169-5417
                Article
                10.1155/2015/130215
                4302382
                f3f3af4b-307f-430f-987f-4272de60ab28
                Copyright © 2015 Shay Keren et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 7 August 2014
                : 22 December 2014
                Categories
                Clinical Study

                Ophthalmology & Optometry
                Ophthalmology & Optometry

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