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Abstract
The origins of neuropeptide Y-like immunoreactive (NPYI) fibers in the paraventricular
and dorsomedial hypothalamic nuclei of the rat were examined using immunohistochemistry.
Destruction of the arcuate nucleus resulted in a marked decrease of NPYI fibers ipsilaterally
in these nuclei, suggesting that most of NPYI fibers in these nuclei originate from
NPYI neurons in the arcuate nucleus. These NPYI systems did not contain noradrenalin.