Kevin Lai: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: Project administration
Catherine A. Harwood: Role: ConceptualizationRole: Funding acquisitionRole: InvestigationRole: ResourcesRole:
SupervisionRole: Writing – review & editing
Karin J. Purdie: Role: ConceptualizationRole: Funding acquisitionRole: InvestigationRole: MethodologyRole:
ResourcesRole: SupervisionRole: Writing – review & editing
Charlotte M. Proby: Role: ConceptualizationRole: Funding acquisitionRole: InvestigationRole: ResourcesRole:
SupervisionRole: Writing – review & editing
Irene M. Leigh: Role: Funding acquisitionRole: ResourcesRole: SupervisionRole: Writing – review &
editing
Namita Ravi: Role: Data curationRole: Formal analysisRole: SoftwareRole: VisualizationRole: Writing
– review & editing
Thaddeus W. Mully: Role: ResourcesRole: Supervision
Lionel Brooks: Role: Formal analysisRole: SoftwareRole: VisualizationRole: Writing – original draft
Priscilla M. Sandoval: Role: VisualizationRole: Writing – original draft
Michael D. Rosenblum: Role: Funding acquisitionRole: ResourcesRole: Supervision
Sarah T. Arron:
ORCID: http://orcid.org/0000-0001-5669-0627
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
MethodologyRole: Project administrationRole: ValidationRole: VisualizationRole: Writing
– original draft
Obul Reddy Bandapalli: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
15
November
2017
Publication date Collection: 2017
Volume: 12
Issue: 11
Electronic Location Identifier: e0188272
Affiliations
[1
]
Department of Dermatology, University of California, San Francisco, California, United
States of America
[2
]
Center for Cutaneous Research and Cell Biology, Barts and the London School of Medicine
and Dentistry, Queen Mary University of London, London, United Kingdom
[3
]
Division of Cancer Research, School of Medicine, University of Dundee, Dundee, United
Kingdom
[4
]
Veterans Administration Medical Center, San Francisco, California, United States of
America
German Cancer Research Center (DKFZ), GERMANY
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-17-21062
DOI: 10.1371/journal.pone.0188272
PMC ID: 5687749
PubMed ID: 29141020
SO-VID: f4a047af-5011-40a3-93da-27d3a92d699d
License:
This is an open access article, free of all copyright, and may be freely reproduced,
distributed, transmitted, modified, built upon, or otherwise used by anyone for any
lawful purpose. The work is made available under the
Creative Commons CC0 public domain dedication.
Funded by: funder-id http://dx.doi.org/10.13039/501100000289, Cancer Research UK;
Award Recipient
:
Irene M. Leigh
This work was funded by Cancer Research UK programme grant to Prof. Irene Leigh and
UCSF Department of Dermatology funding to Dr Sarah Arron.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Connective Tissue Cells
Subject:
Fibroblasts
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Connective Tissue
Subject:
Connective Tissue Cells
Subject:
Fibroblasts
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Connective Tissue
Subject:
Connective Tissue Cells
Subject:
Fibroblasts
Subject:
Biology and life sciences
Subject:
Molecular biology
Subject:
Molecular biology techniques
Subject:
Sequencing techniques
Subject:
RNA sequencing
Subject:
Research and analysis methods
Subject:
Molecular biology techniques
Subject:
Sequencing techniques
Subject:
RNA sequencing
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Epithelial Cells
Subject:
Keratinocytes
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Epithelium
Subject:
Epithelial Cells
Subject:
Keratinocytes
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Epithelium
Subject:
Epithelial Cells
Subject:
Keratinocytes
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancers and Neoplasms
Subject:
Sarcomas
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Mutation
Subject:
Somatic Mutation
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Mutation
Subject:
Nonsense Mutation
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Fusion