For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
28
views
68
references
 Top references
cited by
140
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      285
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Electrospun Fibrous Scaffolds for Tissue Engineering: Viewpoints on Architecture and Fabrication

      review-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Electrospinning has been used for the fabrication of extracellular matrix (ECM)-mimicking fibrous scaffolds for several decades. Electrospun fibrous scaffolds provide nanoscale/microscale fibrous structures with interconnecting pores, resembling natural ECM in tissues, and showing a high potential to facilitate the formation of artificial functional tissues. In this review, we summarize the fundamental principles of electrospinning processes for generating complex fibrous scaffold geometries that are similar in structural complexity to the ECM of living tissues. Moreover, several approaches for the formation of three-dimensional fibrous scaffolds arranged in hierarchical structures for tissue engineering are also presented.

          Related collections

          Most cited references68

          • Record: found
          • Abstract: not found
          • Article: not found

          Biomimetic porous scaffolds for bone tissue engineering

          Shuilin Wu, Xiangmei Liu, Kelvin W.K. Yeung … (2014)
          Article 0 comments Cited 225 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            A decade of progress in tissue engineering.

            Ali Khademhosseini, Robert Langer (2016)
            Tremendous progress has been achieved in the field of tissue engineering in the past decade. Several major challenges laid down 10 years ago, have been studied, including renewable cell sources, biomaterials with tunable properties, mitigation of host responses, and vascularization. Here we review advancements in these areas and envision directions of further development.
            Article 0 comments Cited 206 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: found
              Is Open Access

              Ultrafast laser processing of materials: from science to industry

              Mangirdas Malinauskas, Albertas Žukauskas, Satoshi Hasegawa … (2016)
              Processing of materials by ultrashort laser pulses has evolved significantly over the last decade and is starting to reveal its scientific, technological and industrial potential. In ultrafast laser manufacturing, optical energy of tightly focused femtosecond or picosecond laser pulses can be delivered to precisely defined positions in the bulk of materials via two-/multi-photon excitation on a timescale much faster than thermal energy exchange between photoexcited electrons and lattice ions. Control of photo-ionization and thermal processes with the highest precision, inducing local photomodification in sub-100-nm-sized regions has been achieved. State-of-the-art ultrashort laser processing techniques exploit high 0.1–1 μm spatial resolution and almost unrestricted three-dimensional structuring capability. Adjustable pulse duration, spatiotemporal chirp, phase front tilt and polarization allow control of photomodification via uniquely wide parameter space. Mature opto-electrical/mechanical technologies have enabled laser processing speeds approaching meters-per-second, leading to a fast lab-to-fab transfer. The key aspects and latest achievements are reviewed with an emphasis on the fundamental relation between spatial resolution and total fabrication throughput. Emerging biomedical applications implementing micrometer feature precision over centimeter-scale scaffolds and photonic wire bonding in telecommunications are highlighted.
              Article 0 comments Cited 190 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Int J Mol Sci
                Journal ID (iso-abbrev): Int J Mol Sci
                Journal ID (publisher-id): ijms
                Title: International Journal of Molecular Sciences
                Publisher: MDPI
                ISSN (Electronic): 1422-0067
                Publication date (Electronic): 06 March 2018
                Publication date Collection: March 2018
                Volume: 19
                Issue: 3
                Electronic Location Identifier: 745
                Affiliations
                [1 ]Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford OX3 7LD, UK; indong.jun@ 123456ndorms.ox.ac.uk (I.J.); hyungseop.han@ 123456ndorms.ox.ac.uk (H.-S.H.); james.edwards@ 123456ndorms.ox.ac.uk (J.R.E.)
                [2 ]Center for Biomaterials, Korea Institute of Science & Technology (KIST), Seoul 02792, Korea
                [3 ]Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Korea
                Author notes
                [* ]Correspondence: jeonhj@ 123456kist.re.kr ; Tel.: +82-2-958-5140
                Article
                Publisher ID: ijms-19-00745
                DOI: 10.3390/ijms19030745
                PMC ID: 5877606
                PubMed ID: 29509688
                SO-VID: f53e438a-206b-4824-8f78-be81c5734bf7
                Copyright © © 2018 by the authors.
                License:

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                Date received : 15 November 2017
                Date accepted : 03 March 2018
                Categories
                Subject: Review

                ScienceOpen disciplines: Molecular biology
                Keywords: electrospinning,nanofiber scaffolds,tissue engineering,extracellular matrix-mimicking geometries
                Data availability:
                ScienceOpen disciplines: Molecular biology
                Keywords: electrospinning, nanofiber scaffolds, tissue engineering, extracellular matrix-mimicking geometries

                Comments

                Comment on this article

                scite_

                Similar content285

                See all similar

                Cited by138

                See all cited by

                Most referenced authors947

                See all reference authors