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      Brillouin Light Scattering: Applications in Biomedical Sciences

      review-article
      , ,
      Chemical Reviews
      American Chemical Society

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          Abstract

          Brillouin spectroscopy and imaging are emerging techniques in analytical science, biophotonics, and biomedicine. They are based on Brillouin light scattering from acoustic waves or phonons in the GHz range, providing a nondestructive contactless probe of the mechanics on a microscale. Novel approaches and applications of these techniques to the field of biomedical sciences are discussed, highlighting the theoretical foundations and experimental methods that have been developed to date. Acknowledging that this is a fast moving field, a comprehensive account of the relevant literature is critically assessed here.

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          Most cited references104

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          Berechnung der Fließgrenze von Mischkristallen auf Grund der Plastizitätsbedingung für Einkristalle .

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            Scaling the microrheology of living cells.

            We report a scaling law that governs both the elastic and frictional properties of a wide variety of living cell types, over a wide range of time scales and under a variety of biological interventions. This scaling identifies these cells as soft glassy materials existing close to a glass transition, and implies that cytoskeletal proteins may regulate cell mechanical properties mainly by modulating the effective noise temperature of the matrix. The practical implications are that the effective noise temperature is an easily quantified measure of the ability of the cytoskeleton to deform, flow, and reorganize.
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              Ueber die Beziehung zwischen den beiden Elasticitätsconstanten isotroper Körper

              W Voigt (1889)
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                Author and article information

                Journal
                Chem Rev
                Chem. Rev
                cr
                chreay
                Chemical Reviews
                American Chemical Society
                0009-2665
                1520-6890
                01 May 2019
                10 July 2019
                : 119
                : 13
                : 7833-7847
                Affiliations
                []School of Physics and Astronomy, University of Exeter , Stocker Road, EX4 4QL Exeter, U.K.
                []Department of Physics and Geology, University of Perugia , via Alessandro Pascoli, I-06123 Perugia, Italy
                Author notes
                Article
                10.1021/acs.chemrev.9b00019
                6624783
                31042024
                f58bf7c1-727b-46bd-ba43-0d432d48fb61
                Copyright © 2019 American Chemical Society

                This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.

                History
                : 09 January 2019
                Categories
                Review
                Custom metadata
                cr9b00019
                cr-2019-00019f

                Chemistry
                Chemistry

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