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Wilms tumor gene 1 (WT1), TP53, RAS/BRAF and KIT aberrations in testicular germ cell tumors
L. Boublikova ,
V. Bakardjieva-Mihaylova ,
K. Skvarova Kramarzova ,
D. Kuzilkova ,
A. Dobiasova ,
K. Fiser ,
J. Stuchly ,
M. Kotrova ,
T. Buchler ,
P. Dusek ,
M. Grega ,
B. Rosova ,
Z. Vernerova ,
P. Klezl ,
M. Pesl ,
R. Zachoval ,
M. Krolupper ,
M. Kubecova ,
V. Stahalova ,
J. Abrahamova ,
M. Babjuk ,
R. Kodet ,
J. Trka
July 2016
July 2016
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Abstract
Wilms tumor gene 1 (WT1), a zinc-finger transcription factor essential for testis
development and function, along with other genes, was investigated for their role
in the pathogenesis of testicular germ cell tumors (TGCT).