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      Temporal epilepsy lesions may be detected by the voxel-based quantitative analysis of brain FDG-PET images using an original block-matching normalization software.

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          Abstract

          Statistical parametric mapping (SPM) provides useful voxel-by-voxel analyses of brain images from (18)F-fluorodesoxyglucose positron emission tomography (FDG-PET) after an initial step of spatial normalization through an anatomical template model. In the setting of the preoperative workup of patients with temporal epilepsy, this study aimed at assessing a block-matching (BM) normalization method, where most transformations are computed through small blocks, a principle that minimizes artefacts and overcomes additional image-filtering.

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          Author and article information

          Journal
          Ann Nucl Med
          Annals of nuclear medicine
          Springer Science and Business Media LLC
          1864-6433
          0914-7187
          May 2016
          : 30
          : 4
          Affiliations
          [1 ] Department of Nuclear Medicine and Nancyclotep Imaging Platform, CHU-Nancy, 54000, Nancy, France. a.verger@chu-nancy.fr.
          [2 ] INSERM, IADI U947, 5400, Nancy, France. a.verger@chu-nancy.fr.
          [3 ] Lorraine-University, 54000, Nancy, France. a.verger@chu-nancy.fr.
          [4 ] Department of Nuclear Medicine and Nancyclotep Imaging Platform, CHU-Nancy, 54000, Nancy, France.
          [5 ] Department of Nuclear Medicine, AP-HM, Hospital "La Timone", 13000, Marseille, France.
          [6 ] CNRS UMR7289, Institut de Neurosciences de la Timone, INT, 13000, Marseille, France.
          [7 ] Lorraine-University, 54000, Nancy, France.
          [8 ] Department of Neurology, CHU-Nancy, 54000, Nancy, France.
          [9 ] INRIA Sophia Antipolis-Méditerranée, 06902, Sophia Antipolis, France.
          [10 ] CIC-IT, CHU Nancy, 5400, Nancy, France.
          [11 ] INSERM, CIC-IP 1433, 5400, Nancy, France.
          [12 ] INSERM, U1116, 54000, Nancy, France.
          Article
          10.1007/s12149-016-1060-4
          10.1007/s12149-016-1060-4
          26841946
          f7bf254f-e49c-4db4-a5f0-9d3a8ebc49ce
          History

          Block-matching algorithm,FDG-PET,Mesial temporal lobe epilepsy,Spatial normalization,Statistical parametric mapping

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