Photoreceptor and post-photoreceptoral contributions to photopic ERG a-wave in rhodopsin P347L transgenic rabbits.

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Abstract

The a-wave of the photopic electroretinogram (ERG) of macaque monkeys is made up of the electrical activities of cone photoreceptors and post-photoreceptoral neurons. However, it is not known whether the contributions of these two components change in retinas with inherited photoreceptor degeneration. The purpose of this study was to determine the contributions of cones and post-photoreceptoral neurons to the a-wave of the photopic ERGs in rhodopsin Pro347Leu transgenic (Tg) rabbits.

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Journal

Journal ID (iso-abbrev): Invest. Ophthalmol. Vis. Sci.

Title: Investigative ophthalmology & visual science

Publisher: Association for Research in Vision and Ophthalmology (ARVO)

ISSN (Electronic): 1552-5783

ISSN (Print): 0146-0404

Publication date (Electronic): Mar 15 2012

Volume: 53

Issue: 3

Affiliations

[1 ] Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Article

Publisher Item ID: iovs.11-9006

DOI: 10.1167/iovs.11-9006

PubMed ID: 22273723

SO-VID: f7eeb6eb-f007-4aa9-a6c6-7cdb4895ba84

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