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      End Criteria for Reaching Maximal Oxygen Uptake Must Be Strict and Adjusted to Sex and Age: A Cross-Sectional Study

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          Abstract

          Objective

          To describe different end criteria for reaching maximal oxygen uptake (VO 2max) during a continuous graded exercise test on the treadmill, and to explore the manner by which different end criteria have an impact on the magnitude of the VO 2max result.

          Methods

          A sample of 861 individuals (390 women) aged 20–85 years performed an exercise test on a treadmill until exhaustion. Gas exchange, heart rate, blood lactate concentration and Borg Scale 6–20 rating were measured, and the impact of different end criteria on VO 2max was studied;VO 2 leveling off, maximal heart rate (HR max), different levels of respiratory exchange ratio (RER), and postexercise blood lactate concentration.

          Results

          Eight hundred and four healthy participants (93%) fulfilled the exercise test until voluntary exhaustion. There were no sex-related differences in HR max, RER, or Borg Scale rating, whereas blood lactate concentration was 18% lower in women ( P<0.001). Forty-two percent of the participants achieved a plateau in VO 2; these individuals had 5% higher ventilation ( P = 0.033), 4% higher RER ( P<0.001), and 5% higher blood lactate concentration ( P = 0.047) compared with participants who did not reach a VO 2 plateau. When using RER ≥1.15 or blood lactate concentration ≥8.0 mmol•L –1, VO 2max was 4% ( P = 0.012) and 10% greater ( P<0.001), respectively. A blood lactate concentration ≥8.0 mmol•L –1 excluded 63% of the participants in the 50–85-year-old cohort.

          Conclusions

          A range of typical end criteria are presented in a random sample of subjects aged 20–85 years. The choice of end criteria will have an impact on the number of the participants as well as the VO 2max outcome. Suggestions for new recommendations are given.

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          Most cited references27

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          Maximal oxygen intake as an objective measure of cardio-respiratory performance.

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            An experimental study of physical fitness of Air Force personnel.

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              Predicted values for clinical exercise testing.

              Following thorough evaluation at rest, 265 of 400 current or ex-shipyard workers rode a cycle ergometer with equal work increments each minute to exhaustion while continuous multiple noninvasive cardiorespiratory measures and intermittent intra-arterial blood pressure and blood gas measures were made. Seventy-seven men, with a mean age of 54, including some who were smokers, obese, or hypertensive, were judged to have normal cardiorespiratory systems based on history, physical, electrocardiogram during rest and exercise, chest X-ray, pulmonary function tests, and exercise performance. Their responses to exercise are given. It was unusual to find at maximal exercise a breathing reserve less than 11 L/min, arterial PO2 less than 80 mm Hg, alveolar-arterial PO2 difference greater than 38 mm Hg, arterial-end tidal PCO2 difference greater than 1 mm Hg, respiratory frequency greater than 60, or a dead space/tidal volume ratio greater than 0.28. The normal anaerobic threshold/maximal O2 uptake ratio exceeded 40%. With maximal exercise, the intra-arterial systolic and diastolic pressures rose an average of 68 and 13 mm Hg, respectively. For predicting maximal oxygen uptake and oxygen pulse in an overweight man, we find it preferable to use age and height rather than age and weight.
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                Author and article information

                Contributors
                Role: Editor
                Journal
                PLoS One
                PLoS ONE
                plos
                plosone
                PLoS ONE
                Public Library of Science (San Francisco, USA )
                1932-6203
                2014
                14 January 2014
                : 9
                : 1
                : e85276
                Affiliations
                [1 ]Norwegian School of Sport Sciences, Department of Sports Medicine, Oslo, Norway
                [2 ]Oslo University Hospital, Ullevål, Department of Pulmonary Medicine, Oslo, Norway
                Oregon Health & Science University, United States of America
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                Conceived and designed the experiments: EE SAA. Performed the experiments: EE. Analyzed the data: EE EH SAA. Contributed reagents/materials/analysis tools: EE EH SAA. Wrote the paper: EE EH SAA. Was active in the planning of the study: EE SAA. Controlled the quality of the test procedures:EE EH. Collected, analyzed and interpreting the data: EE EH SAA. Drafted the manuscript: EE.

                Article
                PONE-D-13-29063
                10.1371/journal.pone.0085276
                3891752
                24454832
                fb6b2315-ac57-45f9-afe2-8698135ffed6
                Copyright @ 2014

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 15 July 2013
                : 25 November 2013
                Page count
                Pages: 8
                Funding
                This study was founded by the Norwegian Directorate of Health. The founder had no role in study design, data collection and analysis, preparation of the manuscript or decision to publish.
                Categories
                Research Article
                Biology
                Population Biology
                Aging
                Medicine
                Anatomy and Physiology
                Cardiovascular System
                Musculoskeletal System
                Physiological Processes
                Respiratory System
                Clinical Research Design
                Cohort Studies
                Cross-Sectional Studies
                Reporting Guidelines
                Sports and Exercise Medicine

                Uncategorized
                Uncategorized

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