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      Chronic infections and coronary heart disease: is there a link?

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      The Lancet
      Elsevier BV

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          Abstract

          A large number of studies have reported on associations of human coronary heart disease (CHD) and certain persistent bacterial and viral infections. We review the epidemiological and clinical evidence on CHD and Helicobacter pylori, Chlamydia pneumoniae, and cytomegalovirus (CMV), as well as possible mechanisms. The association between CHD and H pylori may be accounted for by residual confounding from risk factors. Although the association between C pneumoniae and CHD is stronger, the sequence of infection and disease is uncertain. As regards CMV, a limited number of patients with classic atherosclerotic coronary artery disease have been studied. Further studies are needed to resolve these uncertainties.

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          Author and article information

          Journal
          The Lancet
          The Lancet
          Elsevier BV
          01406736
          August 1997
          August 1997
          : 350
          : 9075
          : 430-436
          Article
          10.1016/S0140-6736(97)03079-1
          9259669
          fb7a15ac-0011-43e2-97f9-8863dc501bc6
          © 1997

          https://www.elsevier.com/tdm/userlicense/1.0/

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