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Sensing nickel. NikRs with two pockets.

Publication date: 2002-09-30

Keywords: Bacillus subtilis, metabolism, Binding Sites, Escherichia coli, Escherichia coli Proteins, Gene Expression Regulation, Bacterial, drug effects, Kinetics, Nickel, pharmacology, Protein Binding, Repressor Proteins, Urease

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Abstract

NikR represses expression of a nickel transporter in response to elevated levels of Ni(II). Recent results suggest that repression is elicited by binding of nickel to a high-affinity site, but a low-affinity binding pocket may also play a role.

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PubMed ID:: 12401490

ScienceOpen disciplines: Chemistry

Keywords: Bacillus subtilis,metabolism,Binding Sites,Escherichia coli,Escherichia coli Proteins,Gene Expression Regulation, Bacterial,drug effects,Kinetics,Nickel,pharmacology,Protein Binding,Repressor Proteins,Urease

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ScienceOpen disciplines: Chemistry

Sensing nickel. NikRs with two pockets.

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Drug_transporters

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