Do withdrawal-like symptoms mediate increased marijuana smoking in individuals treated with venlafaxine-XR?

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Abstract

Cannabis-dependent participants with depressive disorder are less likely to achieve abstinence with venlafaxine-XR (VEN-XR) treatment. Individuals on VEN-XR reported more severe withdrawal, despite not reducing their smoking behavior. We hypothesized that withdrawal-like symptoms, likely medication side effects, led to continued marijuana smoking in this group.

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Journal

Journal ID (iso-abbrev): Drug Alcohol Depend

Title: Drug and alcohol dependence

Publisher: Elsevier BV

ISSN (Electronic): 1879-0046

ISSN (Print): 0376-8716

Publication date (Electronic): Nov 01 2014

Volume: 144

Affiliations

[1 ] New York State Psychiatric Institute, Division of Substance Abuse, 1051 Riverside Drive, New York, NY 10032, USA; Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 630 West 168th Street, New York, NY 10032, USA. Electronic address: mak2102@columbia.edu.

[2 ] Department of Biostatistics, Columbia University, 722 West 168th Street, New York, NY 10032, USA.

[3 ] Division of Biostatistics in the Department of Psychiatry, 722 West 168th Street, New York, NY 10032, USA.

[4 ] New York State Psychiatric Institute, Division of Substance Abuse, 1051 Riverside Drive, New York, NY 10032, USA; Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 630 West 168th Street, New York, NY 10032, USA.

Article

Publisher Item ID: S0376-8716(14)00967-3 Mid ID: NIHMS637561

DOI: 10.1016/j.drugalcdep.2014.06.040

PMC ID: 4252763

PubMed ID: 25283697

SO-VID: fea74e44-d969-4186-99ba-1f3cb1eb744b

History

Keywords: Marijuana,Marijuana Withdrawal,Treatment,Venlafaxine,Cannabis,Cannabis Withdrawal

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Keywords: Marijuana, Marijuana Withdrawal, Treatment, Venlafaxine, Cannabis, Cannabis Withdrawal

Do withdrawal-like symptoms mediate increased marijuana smoking in individuals treated with venlafaxine-XR?

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