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      Risk of COVID 19 in patients with inflammatory bowel diseases compared to a control population.

      Author(s): 1 , 2 , 3 , 4 , 4 , 5 , 3 , 6 , 7 , 8 , 9 , 10 , 11 , 3 , 3 , 3 , 12 , 6 , 7 , 10 , 3 , 13 , 14 , 3
      Publication date (Electronic):
      Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
      Publisher: Elsevier BV
      Keywords: COVID-19, Inflammatory bowel disease, Symptoms

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          Abstract

          It is unclear whether patients with inflammatory bowel disease (IBD) are at increased risk of COVID-19.

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          Most cited references35

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          Clinical Characteristics of Coronavirus Disease 2019 in China

          Wei-jie Guan, Zheng-yi Ni, Yu Hu … (2020)
          Abstract Background Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of the affected patients. Methods We extracted data regarding 1099 patients with laboratory-confirmed Covid-19 from 552 hospitals in 30 provinces, autonomous regions, and municipalities in mainland China through January 29, 2020. The primary composite end point was admission to an intensive care unit (ICU), the use of mechanical ventilation, or death. Results The median age of the patients was 47 years; 41.9% of the patients were female. The primary composite end point occurred in 67 patients (6.1%), including 5.0% who were admitted to the ICU, 2.3% who underwent invasive mechanical ventilation, and 1.4% who died. Only 1.9% of the patients had a history of direct contact with wildlife. Among nonresidents of Wuhan, 72.3% had contact with residents of Wuhan, including 31.3% who had visited the city. The most common symptoms were fever (43.8% on admission and 88.7% during hospitalization) and cough (67.8%). Diarrhea was uncommon (3.8%). The median incubation period was 4 days (interquartile range, 2 to 7). On admission, ground-glass opacity was the most common radiologic finding on chest computed tomography (CT) (56.4%). No radiographic or CT abnormality was found in 157 of 877 patients (17.9%) with nonsevere disease and in 5 of 173 patients (2.9%) with severe disease. Lymphocytopenia was present in 83.2% of the patients on admission. Conclusions During the first 2 months of the current outbreak, Covid-19 spread rapidly throughout China and caused varying degrees of illness. Patients often presented without fever, and many did not have abnormal radiologic findings. (Funded by the National Health Commission of China and others.)
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            Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

            Safiya Richardson, Jamie Hirsch, Mangala Narasimhan … (2020)
            There is limited information describing the presenting characteristics and outcomes of US patients requiring hospitalization for coronavirus disease 2019 (COVID-19).
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              Real-time tracking of self-reported symptoms to predict potential COVID-19

              Cristina Menni, Ana M. Valdes, Maxim Freidin … (2020)
              A total of 2,618,862 participants reported their potential symptoms of COVID-19 on a smartphone-based app. Among the 18,401 who had undergone a SARS-CoV-2 test, the proportion of participants who reported loss of smell and taste was higher in those with a positive test result (4,668 of 7,178 individuals; 65.03%) than in those with a negative test result (2,436 of 11,223 participants; 21.71%) (odds ratio = 6.74; 95% confidence interval = 6.31–7.21). A model combining symptoms to predict probable infection was applied to the data from all app users who reported symptoms (805,753) and predicted that 140,312 (17.42%) participants are likely to have COVID-19.
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                Author and article information

                Journal
                Journal ID (iso-abbrev): Dig Liver Dis
                Title: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
                Publisher: Elsevier BV
                ISSN (Electronic): 1878-3562
                ISSN (Print): 1590-8658
                Publication date (Electronic): March 2021
                Volume: 53
                Issue: 3
                Affiliations
                [1 ] Gastroenterology Unit, ASST Fatebenefratelli Sacco, Department of Biomedical and Clinical Sciences "L.Sacco" University of Milan, Italy. Electronic address: giovanni.maconi@unimi.it.
                [2 ] Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
                [3 ] Gastroenterology Unit, ASST Fatebenefratelli Sacco, Department of Biomedical and Clinical Sciences "L.Sacco" University of Milan, Italy.
                [4 ] Department of Gastroenterology, Monash Health. Faculty of Medicine, Nursing & Health Sciences, Monash University, Clayton, Victoria, Australia.
                [5 ] Gastroenterology Unit, IRCCS Policlinico San Donato, San Donato Milanese, Italy; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.
                [6 ] Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Università degli Studi di Pavia, Pavia, Lombardia, Italy.
                [7 ] Gastroenterology Unit, Rho Hospital, Rho (MI), ASST Rhodense, Garbagnate Milanese, Italy.
                [8 ] Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy; Division of Gastroenterology, ASST Spedali Civili, Brescia, Italy.
                [9 ] Papa Giovanni XXIII Hospital, Gastroenterology and Digestive Endoscopy Units, Bergamo, Italy.
                [10 ] Department of Gastroenterology and Endoscopy, Maggiore Hospital, ASST Crema, Crema, Italy.
                [11 ] Internal Medicine and Gastroenterology, Codogno Hospital, Italy.
                [12 ] Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.
                [13 ] I Division of Infectious Diseases, ASST Fatebenefratelli-Sacco, L. Sacco Hospital, Milan, Italy.
                [14 ] III Division of Infectious Diseases, ASST Fatebenefratelli-Sacco, Department of Biomedical and Clinical Sciences, University of Milan, Italy.
                Article
                Publisher Item ID: S1590-8658(20)31093-8
                DOI: 10.1016/j.dld.2020.12.013
                PMC ID: 7762705
                PubMed ID: 33483259
                SO-VID: 403e307a-e2a1-44f9-9400-0cbdcc662736
                History

                Keywords: Symptoms,COVID-19,Inflammatory bowel disease
                Data availability:
                Keywords: Symptoms, COVID-19, Inflammatory bowel disease

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