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      Detection rate of FNA cytology in medullary thyroid carcinoma: a meta-analysis.

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          Abstract

          The early detection of medullary thyroid carcinoma (MTC) can improve patient prognosis, because histological stage and patient age at diagnosis are highly relevant prognostic factors. As a consequence, delay in the diagnosis and/or incomplete surgical treatment should correlate with a poorer prognosis for patients. Few papers have evaluated the specific capability of fine-needle aspiration cytology (FNAC) to detect MTC, and small series have been reported. This study conducts a meta-analysis of published data on the diagnostic performance of FNAC in MTC to provide more robust estimates.

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          Author and article information

          Journal
          Clin. Endocrinol. (Oxf)
          Clinical endocrinology
          1365-2265
          0300-0664
          Feb 2015
          : 82
          : 2
          Affiliations
          [1 ] Section of Endocrinology and Diabetology, Ospedale Israelitico, Rome, Italy; Department of Nuclear Medicine and Thyroid Centre, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
          Article
          10.1111/cen.12563
          25047365
          b6dee8ce-60e2-4e6e-a105-775b102f70cf
          © 2014 John Wiley & Sons Ltd.
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