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      Adherence to antiretroviral therapy and retention in care for adolescents living with HIV from 10 districts in Uganda.

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          Abstract

          Adolescents have gained increased attention because they are the only age group where HIV related mortality is going up. We set out to describe the level and factors associated with adherence to antiretroviral therapy (ART) as well as the 1 year retention in care among adolescents in 10 representative districts in Uganda. In addition, we explored the barriers and facilitators of adherence to ART among adolescents.

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          Non-adherence to highly active antiretroviral therapy predicts progression to AIDS.

          Neil R. Clark, D Bangsberg, Andrew Zolopa … (2001)
          Article 0 comments Cited 179 times – based on 0 reviews     Review now
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            Global Report UNAIDS report on the global AIDS epidemic 2013

            (2013)
            Article 0 comments Cited 123 times – based on 0 reviews     Review now
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              Disclosure of HIV status and adherence to daily drug regimens among HIV-infected children in Uganda.

              Winnie Bikaako-Kajura, Emmanuel Luyirika, David Purcell … (2006)
              Pediatric adherence to daily drug regimens has not been widely assessed in Africa where majority of HIV infected children live. Using in-depth interviews of 42 HIV-infected children taking ART and/or cotrimoxazole prophylaxis, and 42 primary caregivers, at a comprehensive HIV/AIDS clinic in Uganda, we evaluated their adherence experiences for purposes of program improvement. Daily drug regimens provided by the pediatric clinic included cotrimoxazole prophylaxis as well as ART and cotrimoxazole combined. Complete disclosure of HIV status by caregivers to children and strong parental relationships were related to good adherence. Structural factors including poverty and stigma were barriers to adherence even for children who had had complete disclosure and a supportive relationship with a parent. To ensure adherence to life-extending medications, our findings underscore the need for providers to support caregivers to disclose, provide on-going support and maintain open communication with HIV-infected children taking cotrimoxazole prophylaxis and ART.
              Article 0 comments Cited 94 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (iso-abbrev): BMC Infect. Dis.
                Title: BMC infectious diseases
                Publisher: Springer Science and Business Media LLC
                ISSN (Electronic): 1471-2334
                ISSN (Print): 1471-2334
                Publication date (Electronic): Nov 14 2015
                Volume: 15
                Affiliations
                [1 ] Department of Paediatrics and Child Health, School of Medicine, Makerere University College of Health Sciences, P O Box 7062, Kampala, Uganda. nicolettebarungi@yahoo.com.
                [2 ] AIDS Control Program, Ministry of Health, Kampala, Uganda. ellypj@yahoo.co.uk.
                [3 ] AIDS Control Program, Ministry of Health, Kampala, Uganda. barbaraasire@yahoo.com.
                [4 ] AIDS Control Program, Ministry of Health, Kampala, Uganda. ckatureebe@urc-chs.com.
                [5 ] AIDS Control Program, Ministry of Health, Kampala, Uganda. luanzag@gmail.com.
                [6 ] AIDS Control Program, Ministry of Health, Kampala, Uganda. eleanormagongo@gmail.com.
                [7 ] AIDS Control Program, Ministry of Health, Kampala, Uganda. jmusinguzi@infocom.co.ug.
                [8 ] Department of Community Health and Behavioral Sciences, School of Public Health, Makerere University College of Health Sciences, Kampala, Uganda. atuyambe@musph.ac.ug.
                [9 ] USAID SUSTAIN Project, University Research Co., LLC, Kampala, Uganda. ntumwesigye@gmail.com.
                Article
                Publisher Item ID: 10.1186/s12879-015-1265-5
                DOI: 10.1186/s12879-015-1265-5
                PMC ID: 4647509
                PubMed ID: 26573923
                SO-VID: f037f5db-0ce2-490c-a353-8e87c27cfb5b
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