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      Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease.

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          Abstract

          Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and likely includes a subgroup that is biologically comparable to asthma. Studying asthma-associated gene expression changes in COPD could add insight into COPD pathogenesis and reveal biomarkers that predict a favorable response to corticosteroids.

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          Author and article information

          Journal
          Am. J. Respir. Crit. Care Med.
          American journal of respiratory and critical care medicine
          1535-4970
          1073-449X
          Apr 1 2015
          : 191
          : 7
          Affiliations
          [1 ] 1 Department of Medicine, Division of Pulmonary, Critical Care, Allergy, and Sleep and.
          Article
          10.1164/rccm.201408-1458OC
          25611785

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