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      Zinc oxide nanoparticles: a promising nanomaterial for biomedical applications.

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          Abstract

          Zinc oxide (ZnO) nanoparticles (NPs) are a promising platform for use in biomedical research, especially given their anticancer and antimicrobial activities. These activities are associated with the ability of ZnO NPs to generate reactive oxygen species (ROS) and induce apoptosis. In addition, ZnO NPs have been successfully exploited as drug carriers for loading and transporting drugs to target sites, thereby reducing unwanted toxicity and off-target effects, and resulting in amplified synergistic effects. Here, we discuss the synthesis and biomedical applications of ZnO NPs.

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          Author and article information

          Journal
          Drug Discov. Today
          Drug discovery today
          Elsevier BV
          1878-5832
          1359-6446
          December 2017
          : 22
          : 12
          Affiliations
          [1 ] Department of Wood Processing, Mendel University in Brno, Brno, Czech Republic.
          [2 ] Department of Pharmaceutics, Jamia Hamdard, New Delhi, India.
          [3 ] Department of Production Management and Engineering, Warsaw University of Life Sciences, Faculty of Production Engineering, Warsaw, Poland.
          [4 ] School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA. Electronic address: bhuvanvaidya@gmail.com.
          Article
          S1359-6446(17)30077-6
          10.1016/j.drudis.2017.08.006
          28847758
          0c03218c-bb4c-4510-99e6-069f5eaeea38
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