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      Early implementation of protective measures defines surgical outcomes in the COVID-19 pandemic

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          Abstract

          Quick implementation of specific protocols and protective measures in a tertiary hospital in Spain allowed for the early diagnosis and optimal management of patients with SARS-CoV-2 infection and proper protection of staff and inpatients. From the COVID-19 outbreak in this country until the time of writing, 14 patients in our hospital underwent surgery with COVID-19, or COVID-19 developed postoperatively. Their postoperative outcomes did not differ from those in our routine clinical practice, with a 0% respiratory failure rate and a 7.14% mortality rate, in contrast with other published series. COVID-19 did not develop in any of the healthcare workers present in the operating room during these procedures or in those who cared for these patients on the ward.

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          A Novel Coronavirus from Patients with Pneumonia in China, 2019

          Na Zhu, Dingyu Zhang, Wenling Wang … (2020)
          Summary In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily. Different from both MERS-CoV and SARS-CoV, 2019-nCoV is the seventh member of the family of coronaviruses that infect humans. Enhanced surveillance and further investigation are ongoing. (Funded by the National Key Research and Development Program of China and the National Major Project for Control and Prevention of Infectious Disease in China.)
          Article 0 comments Cited 12802 times – based on 0 reviews     Review now
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            Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

            Zunyou Wu, Jennifer M. McGoogan (2020)
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              Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases

              Tao Ai, Zhenlu Yang, Hongyan Hou … (2020)
              Background Chest CT is used for diagnosis of 2019 novel coronavirus disease (COVID-19), as an important complement to the reverse-transcription polymerase chain reaction (RT-PCR) tests. Purpose To investigate the diagnostic value and consistency of chest CT as compared with comparison to RT-PCR assay in COVID-19. Methods From January 6 to February 6, 2020, 1014 patients in Wuhan, China who underwent both chest CT and RT-PCR tests were included. With RT-PCR as reference standard, the performance of chest CT in diagnosing COVID-19 was assessed. Besides, for patients with multiple RT-PCR assays, the dynamic conversion of RT-PCR results (negative to positive, positive to negative, respectively) was analyzed as compared with serial chest CT scans for those with time-interval of 4 days or more. Results Of 1014 patients, 59% (601/1014) had positive RT-PCR results, and 88% (888/1014) had positive chest CT scans. The sensitivity of chest CT in suggesting COVID-19 was 97% (95%CI, 95-98%, 580/601 patients) based on positive RT-PCR results. In patients with negative RT-PCR results, 75% (308/413) had positive chest CT findings; of 308, 48% were considered as highly likely cases, with 33% as probable cases. By analysis of serial RT-PCR assays and CT scans, the mean interval time between the initial negative to positive RT-PCR results was 5.1 ± 1.5 days; the initial positive to subsequent negative RT-PCR result was 6.9 ± 2.3 days). 60% to 93% of cases had initial positive CT consistent with COVID-19 prior (or parallel) to the initial positive RT-PCR results. 42% (24/57) cases showed improvement in follow-up chest CT scans before the RT-PCR results turning negative. Conclusion Chest CT has a high sensitivity for diagnosis of COVID-19. Chest CT may be considered as a primary tool for the current COVID-19 detection in epidemic areas. A translation of this abstract in Farsi is available in the supplement. - ترجمه چکیده این مقاله به فارسی، در ضمیمه موجود است.
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                Author and article information

                Contributors
                Ana Senent-Boza:
                ORCID: http://orcid.org/0000-0002-0033-5850
                asenentboza@gmail.com
                Journal
                Journal ID (nlm-ta): Surg Today
                Journal ID (iso-abbrev): Surg. Today
                Title: Surgery Today
                Publisher: Springer Singapore (Singapore )
                ISSN (Print): 0941-1291
                ISSN (Electronic): 1436-2813
                Publication date (Electronic): 22 July 2020
                Pages: 1-6
                Affiliations
                [1 ]GRID grid.411109.c, ISNI 0000 0000 9542 1158, Department of General and Digestive Surgery, , Virgen del Rocio University Hospital, ; Avda. Manuel Siurot s/n, PC 41013 Seville, Spain
                [2 ]GRID grid.411109.c, ISNI 0000 0000 9542 1158, Department of Anesthesiology and Reanimation, , Virgen del Rocio University Hospital, ; Seville, Spain
                [3 ]GRID grid.411109.c, ISNI 0000 0000 9542 1158, Department of Gynecology and Obstetrics, , Virgen del Rocio University Hospital, ; Seville, Spain
                [4 ]GRID grid.9224.d, ISNI 0000 0001 2168 1229, Professor of Surgery, , University of Seville, ; Seville, Spain
                Author information
                http://orcid.org/0000-0002-0033-5850
                Article
                Publisher ID: 2080
                DOI: 10.1007/s00595-020-02080-w
                PMC ID: 7374947
                SO-VID: 0e495998-31c4-40e5-ac96-3ac101f4b143
                Copyright © © Springer Nature Singapore Pte Ltd. 2020
                License:

                This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

                History
                Date received : 4 May 2020
                Date accepted : 14 June 2020
                Categories
                Subject: Short Communication

                ScienceOpen disciplines: Surgery
                Keywords: surgical outcomes,covid-19,sars-cov-2
                Data availability:
                ScienceOpen disciplines: Surgery
                Keywords: surgical outcomes, covid-19, sars-cov-2

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