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Immunogenicity of different brands of human insulin and rapid-acting insulin analogs in insulin-naïve children with type 1 diabetes.
B Mianowska
1 ,
A Szadkowska ,
I Pietrzak ,
A Zmysłowska ,
O Wegner ,
J Tomczonek ,
J Bodalski ,
W Młynarski
Mar 2011
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Abstract
To determine (i) whether insulin preparations produced by three companies induce the same immune responses in insulin-naïve children with type 1 diabetes (T1DM); (ii) if switching from human insulin to rapid-acting insulin analogs influences this immune response; and (iii) if different insulin brands produce different clinical results during the first 2 yr after T1DM diagnosis.