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      New Eco-Friendly 1-Alkyl-3-(4-phenoxybutyl) Imidazolium-Based Ionic Liquids Derivatives: A Green Ultrasound-Assisted Synthesis, Characterization, Antibacterial Activity and POM Analyses

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          Abstract

          In view of the emerging importance of the ILs as “green” materials with wide applications and our general interests in green processes, a series of a twenty five new 1-alkyl-3-(4-phenoxybutyl) imidazolium-based ionic liquids (ILs) derivatives is synthesized using a facile and green ultrasound-assisted procedure. Their structures were characterized by FT-IR, 1H-NMR, 13C-NMR, 11B, 19F, 31P, and mass spectrometry. Antimicrobial screens of some selected ILs were conducted against a panel of Gram-positive and Gram-negative bacteria. The antimicrobial activity of each compound was measured by determination of the minimal inhibitory concentration (MIC) yielding very interesting and promising results. Their antibacterial activities are reported, and, on the basis of the experimental and virtual POM screening data available, attempt is also made to elucidate the structure activity relationship.

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          Most cited references 38

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          Task-Specific Ionic Liquids

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            Toxicity and antimicrobial activity of imidazolium and pyridinium ionic liquids

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              Ionic liquids: solvents for the electrodeposition of metals and semiconductors

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                Author and article information

                Journal
                Molecules
                Molecules
                molecules
                Molecules
                MDPI
                1420-3049
                07 August 2014
                August 2014
                : 19
                : 8
                : 11741-11759
                Affiliations
                [1 ]Department of Chemistry, Taibah University, Al-Madina Al-Mounawara 30002, Saudi Arabia
                [2 ]Laboratoire de Chimie & Electrochimie des Complexes Métalliques (LCECM) USTO-MB, University of Sciences and Technology Mohamed Boudiaf, BP 1505 Oran, El M'nouar, Algeria
                [3 ]Microbiology department, Faculty of Science, Ain Shams University, Cairo 11566, Egypt
                [4 ]Biology Department, Taibah University, Al-Madina Al-Mounawara 30002, Saudi Arabia
                [5 ]Laboratoire de Chimie des Matériaux, Faculté des Sciences, Université Mohammed Premier, Oujda-60000, Morocco
                [6 ]LCAE-URAC18, Faculté des Sciences, Université Mohammed Premier, B.P. 717, Oujda-60000, Morocco
                Author notes
                [* ]Author to whom correspondence should be addressed; E-Mail: mouslim@ 123456mail.be ; Tel.: +966-562-441-572.
                Article
                molecules-19-11741
                10.3390/molecules190811741
                6270970
                25153856
                © 2014 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license ( http://creativecommons.org/licenses/by/3.0/).

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