Flecks in Recessive Stargardt Disease: Short-Wavelength Autofluorescence, Near-Infrared Autofluorescence, and Optical Coherence Tomography.

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Abstract

We evaluated the incongruous observation whereby flecks in recessive Stargardt disease (STGD1) can exhibit increased short-wavelength autofluorescence (SW-AF) that originates from retinal pigment epithelium (RPE) lipofuscin, while near-infrared AF (NIR-AF), emitted primarily from RPE melanin, is usually reduced or absent at fleck positions.

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Journal

Journal ID (iso-abbrev): Invest. Ophthalmol. Vis. Sci.

Title: Investigative ophthalmology & visual science

ISSN (Electronic): 1552-5783

ISSN (Print): 0146-0404

Publication date (Electronic): Jul 2015

Volume: 56

Issue: 8

Affiliations

[1 ] Department of Ophthalmology Columbia University, New York, New York, United States 2Department of Pathology and Cell Biology, Columbia University, New York, New York, United States.

[2 ] Department of Ophthalmology Columbia University, New York, New York, United States.

Article

Publisher Item ID: 2422885

DOI: 10.1167/iovs.15-16763

PMC ID: 4525681

PubMed ID: 26230768

SO-VID: 1fc91ce2-f002-4a20-b743-846dbaa53f12

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