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      MR Imaging Findings of Clonorchiasis

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          Abstract

          Objective

          The purpose of this study was to evaluate the MR spectrum and MR cholangiographic imaging findings of clonorchiasis.

          Materials and Methods

          We reviewed 26 patients with confirmed clonorchiasis by either stool tests (n=24) or surgery (n=2). MR imaging was performed on a 1.5 T system (GE Medical Systems, Milwaukee, WI) with a torso coil. Axial T1- and T2-weighted, gadolinium-enhanced dynamic images and MR cholangiography were obtained. Image analyses were used to identify abnormalities of the intrahepatic and extrahepatic bile ducts and the presence of hepatobiliary malignancy. All MR examinations were reviewed by the consensus of two abdominal radiologists.

          Results

          Intrahepatic bile duct abnormalities were seen in 23 (89%) of the 26 patients. The most common finding was mild dilatation of the intrahepatic bile duct which was found in 21 (81%). "Too many intrahepatic ducts" were found in 16(62%), wall enhancement and thickening in 21 (81%) and filling defects and ductal stricture in the intrahepatic bile duct in 6 (24%) and 3 (12%) patients, respectively. Extrahepatic ductal dilation was found in 5 (19%) and 9 (35%) revealed hepatobiliary malignancy.

          Conclusion

          MR imaging revealed various findings of clonorchiasis, including dilatation, wall enhancement, stricture of the intrahepatic ducts and filling defect within the intrahepatic bile duct.

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          Most cited references26

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          The current pathobiology and chemotherapy of clonorchiasis.

          This special issue is devoted to a review of the current state of knowledge of clonorchiasis. Sections deal with: the biology of Clonorchis sinensis; geographical distribution, with particular regard to Korea; epidemiology; pathogenesis; clinical features; diagnosis; prevention and control; chemotherapy.
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            Biliary dilatation: differentiation of benign from malignant causes--value of adding conventional MR imaging to MR cholangiopancreatography.

            To determine the value of conventional T1 - and T2-weighted images and gadolinium-enhanced dynamic magnetic resonance (MR) images as a supplement to MR cholangiopancreatographic (MRCP) images in differentiation of benign from malignant causes of biliary dilatation. MR studies in 62 patients with biliary dilatation with proved causes included conventional T1- and less heavily T2-weighted images, as well as gadolinium-enhanced dynamic images and heavily T2-weighted MRCP images. Two radiologists reviewed MRCP images alone, MRCP images with nonenhanced T1 - and T2-weighted MR images, and MRCP images with nonenhanced and gadolinium-enhanced dynamic images. For differentiation of benign from malignant causes of biliary dilatation, the area under the receiver operating characteristic curve (A(z)) was significantly (P < .05) larger for MRCP images interpreted with T1 - and T2-weighted images (0.9547 for reader 1, 0.8404 for reader 2) than for MRCP images alone (0.8144 for reader 1, 0.8122 for reader 2). The addition of gadolinium-enhanced dynamic MR images to MRCP images with nonenhanced T1- and T2-weighted images did not significantly increase accuracy (A(z) = 0.9554 for reader 1 and 0.8650 for reader 2), but the level of confidence was increased in 17%-24% of cases. Use of nonenhanced T1- and less heavily T2-weighted images with MRCP images significantly improved the diagnostic accuracy of MR examinations of pancreaticobiliary disease.
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              The relationship between primary carcinoma of the liver and infestation with Clonorchis sinensis.

              P.-Y. Hou (1956)
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                Author and article information

                Journal
                Korean J Radiol
                KJR
                Korean Journal of Radiology
                The Korean Radiological Society
                1229-6929
                2005-8330
                Jan-Mar 2004
                31 March 2004
                : 5
                : 1
                : 25-30
                Affiliations
                [1 ]Department of Diagnostic Radiology, Chonnam National University Medical School, Korea.
                [2 ]Department of Diagnostic Radiology, Namkwang Hospital, Seonam University Medical School, Korea.
                Author notes
                Address reprint requests to: Yong Yeon Jeong, MD, Department of Diagnostic Radiology, Chonnam National University Medical School, 8 Hack-dong, Dong-gu, Gwang-Ju 501-757, Korea. Tel. (8262) 220-5748, Fax. (8262) 226-4380, yjeong@ 123456chonnam.ac.kr
                Article
                10.3348/kjr.2004.5.1.25
                2698110
                15064556
                2620a955-a99c-4883-abf2-e861fe5df36b
                Copyright © 2004 The Korean Radiological Society

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 07 July 2003
                : 05 January 2004
                Categories
                Original Article

                Radiology & Imaging
                bile ducts, diseases,magnetic resonance (mr), cholangiopancreatography,bile ducts, mr,bile ducts, cholangitis

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