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      A Randomized Clinical Trial Comparing Individual Cognitive Behavioral Therapy and Child-Centered Therapy for Child Anxiety Disorders

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          Abstract

          <div class="section"> <a class="named-anchor" id="S1"> <!-- named anchor --> </a> <h5 class="section-title" id="d8560818e208">Objective</h5> <p id="P1">This study compared individual cognitive behavioral therapy (CBT) and a supportive child-centered therapy (CCT) for child anxiety disorders on rates of treatment response and recovery at post-treatment and one-year follow-up, as well as on real-world measures of emotional functioning. </p> </div><div class="section"> <a class="named-anchor" id="S2"> <!-- named anchor --> </a> <h5 class="section-title" id="d8560818e213">Method</h5> <p id="P2">Youth (N= 133; ages 9–14) with anxiety disorders (generalized, separation, and/or social anxiety) were randomized using a 2:1 ratio to CBT ( <i>N</i> = 90) or CCT ( <i>N</i> = 43), which served as an active comparison. Treatment response and recovery at post-treatment and one-year follow-up were assessed by Independent Evaluators, and youth completed ecological momentary assessment (EMA) of daily emotions throughout treatment. </p> </div><div class="section"> <a class="named-anchor" id="S3"> <!-- named anchor --> </a> <h5 class="section-title" id="d8560818e224">Results</h5> <p id="P3">The majority of youth in both CBT and CCT were classified as treatment responders (71.1% for CBT; 55.8% for CCT), but youth treated with CBT were significantly more likely to fully recover, no longer meeting diagnostic criteria for any of the targeted anxiety disorders and no longer showing residual symptoms (66.7% for CBT vs. 46.5% for CCT). Youth treated with CBT also reported significantly lower negative emotions associated with recent negative events experienced in daily life during the latter stages of treatment relative to youth treated with CCT. Furthermore, a significantly higher percentage of youth treated with CBT compared to CCT were in recovery at one-year follow-up (82.2% for CBT vs. 65.1% for CCT). </p> </div><div class="section"> <a class="named-anchor" id="S4"> <!-- named anchor --> </a> <h5 class="section-title" id="d8560818e229">Conclusions</h5> <p id="P4">These findings indicate potential benefits of CBT above and beyond supportive therapy on the breadth, generalizability, and durability of treatment-related gains. </p> </div>

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          Most cited references34

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          10-year research update review: the epidemiology of child and adolescent psychiatric disorders: I. Methods and public health burden.

          To review recent progress in child and adolescent psychiatric epidemiology in the area of prevalence and burden. The literature published in the past decade was reviewed under two headings: methods and findings. Methods for assessing the prevalence and community burden of child and adolescent psychiatric disorders have improved dramatically in the past decade. There are now available a broad range of interviews that generate DSM and ICD diagnoses with good reliability and validity. Clinicians and researchers can choose among interview styles (respondent based, interviewer based, best estimate) and methods of data collection (paper and pencil, computer assisted, interviewer or self-completion) that best meet their needs. Work is also in progress to develop brief screens to identify children in need of more detailed assessment, for use by teachers, pediatricians, and other professionals. The median prevalence estimate of functionally impairing child and adolescent psychiatric disorders is 12%, although the range of estimates is wide. Disorders that often appear first in childhood or adolescence are among those ranked highest in the World Health Organization's estimates of the global burden of disease. There is mounting evidence that many, if not most, lifetime psychiatric disorders will first appear in childhood or adolescence. Methods are now available to monitor youths and to make early intervention feasible.
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            A measure of positive and negative affect for children: Scale development and preliminary validation.

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              Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety.

              Anxiety disorders are common psychiatric conditions affecting children and adolescents. Although cognitive behavioral therapy and selective serotonin-reuptake inhibitors have shown efficacy in treating these disorders, little is known about their relative or combined efficacy. In this randomized, controlled trial, we assigned 488 children between the ages of 7 and 17 years who had a primary diagnosis of separation anxiety disorder, generalized anxiety disorder, or social phobia to receive 14 sessions of cognitive behavioral therapy, sertraline (at a dose of up to 200 mg per day), a combination of sertraline and cognitive behavioral therapy, or a placebo drug for 12 weeks in a 2:2:2:1 ratio. We administered categorical and dimensional ratings of anxiety severity and impairment at baseline and at weeks 4, 8, and 12. The percentages of children who were rated as very much or much improved on the Clinician Global Impression-Improvement scale were 80.7% for combination therapy (P<0.001), 59.7% for cognitive behavioral therapy (P<0.001), and 54.9% for sertraline (P<0.001); all therapies were superior to placebo (23.7%). Combination therapy was superior to both monotherapies (P<0.001). Results on the Pediatric Anxiety Rating Scale documented a similar magnitude and pattern of response; combination therapy had a greater response than cognitive behavioral therapy, which was equivalent to sertraline, and all therapies were superior to placebo. Adverse events, including suicidal and homicidal ideation, were no more frequent in the sertraline group than in the placebo group. No child attempted suicide. There was less insomnia, fatigue, sedation, and restlessness associated with cognitive behavioral therapy than with sertraline. Both cognitive behavioral therapy and sertraline reduced the severity of anxiety in children with anxiety disorders; a combination of the two therapies had a superior response rate. (ClinicalTrials.gov number, NCT00052078.) 2008 Massachusetts Medical Society
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                Author and article information

                Journal
                Journal of Clinical Child & Adolescent Psychology
                Journal of Clinical Child & Adolescent Psychology
                Informa UK Limited
                1537-4416
                1537-4424
                July 17 2017
                March 16 2016
                : 1-13
                Affiliations
                [1 ] Department of Psychology, University of Pittsburgh
                [2 ] Department of Psychiatry, University of Pittsburgh School of Medicine
                [3 ] Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles
                [4 ] School of Public Health, University of California at Berkeley
                [5 ] Department of Psychology, Temple University
                [6 ] Department of Psychiatry, Drexel University College of Medicine
                Article
                10.1080/15374416.2016.1138408
                5218980
                26983904
                2dc7dab0-17c1-4c77-90a5-d8e84bbd3670
                © 2016
                History

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