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COMBINED TREATMENT WITH SAXAGLIPTIN PLUS DAPAGLIFLOZIN REDUCES INSULIN LEVELS BY INCREASED INSULIN CLEARANCE AND IMPROVES β-CELL FUNCTION.
Ella Ekholm ,
Lars Hansen ,
Eva Johnsson ,
Nayyar Iqbal ,
Björn Carlsson ,
Hungta Chen ,
Boaz Hirshberg
Mar 2017
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Abstract
To determine if reduction in serum insulin with dapagliflozin plus saxagliptin or dapagliflozin add-on to metformin contributed to increased insulin clearance and to assess the effects of these treatments on β-cell function.