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Effect of Dietary Changes on Urinary Oxalate Excretion and Calcium Oxalate Supersaturation in Patients With Hyperoxaluric Stone Formation
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Abstract
To test the hypothesis that patients with hyperoxaluria, who modified their dietary
calcium intake, would reduce their urinary oxalate excretion without raising their
urinary calcium excretion. Diet is a major factor in idiopathic calcium oxalate urolithiasis,
yet controversy exists regarding the ideal clinical recommendations. Approximately
20% of patients with calcium oxalate stone formation have hyperoxaluria (> or = 45
mg oxalate/d). Calcium supplements to bind dietary oxalate have been suggested, but
clinical evidence of this therapy is lacking.