Ventilator-related causes of lung injury: the mechanical power.

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Abstract

We hypothesized that the ventilator-related causes of lung injury may be unified in a single variable: the mechanical power. We assessed whether the mechanical power measured by the pressure-volume loops can be computed from its components: tidal volume (TV)/driving pressure (∆P aw), flow, positive end-expiratory pressure (PEEP), and respiratory rate (RR). If so, the relative contributions of each variable to the mechanical power can be estimated.

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Journal

Journal ID (iso-abbrev): Intensive Care Med

Title: Intensive care medicine

ISSN (Electronic): 1432-1238

ISSN (Print): 0342-4642

Publication date (Electronic): Oct 2016

Volume: 42

Issue: 10

Affiliations

[1 ] Department of Anesthesiology, Emergency and Intensive Care Medicine, University of Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany. gattinoniluciano@gmail.com.

[2 ] Department of Anesthesiology, Emergency and Intensive Care Medicine, University of Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.

[3 ] Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Milan, Italy.

[4 ] Dipartimento di Anestesia, Rianimazione, ed Emergenza Urgenza, Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.

[5 ] Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milan, Italy.

Article

Publisher Item ID: 10.1007/s00134-016-4505-2

DOI: 10.1007/s00134-016-4505-2

PubMed ID: 27620287

SO-VID: 31adf68a-0720-49dd-88b1-20e01b7347b3

History

Keywords: ARDS,Mechanical ventilation,Respiratory mechanics,VILI

Data availability:

Keywords: ARDS, Mechanical ventilation, Respiratory mechanics, VILI

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