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      What Ethics for Bioart?

      research-article
      Nanoethics
      Springer Netherlands
      Bioethics, Art and morality, Bioart, Validation, Tissue culture and art project

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          Abstract

          Living artworks created with biotechnology raise a range of ethical questions, some of which are unprecedented, others well known from other contexts. These questions are often discussed within the framework of bioethics, the ethics of the life sciences. The basic concern of institutionalised bioethics is to develop and implement ethical guidelines for ethically responsible handling of living material in technological and scientific contexts. Notably, discussions of ethical issues in bioart do not refer to existing discourses on art and morality from the field of aesthetics. The latter framework is primarily concerned with how the moral value of an artwork affects its artistic value. The author argues that a successful integration of these two frameworks will make possible an ethics of bioart that is adequate to its subject matter and relevant for practice. Such an integrated approach can give increased depth to understandings of ethical issues in bioart, inspire new ways of thinking about ethics in relation to art in general and give novel impulses to bioethics and technology assessment. Artworks by the Tissue Culture and Art Project and their reception serve as the empirical starting point for connecting perspectives in art with those of bioethics, developing an ethics for bioart. The author suggests that consideration of the effect of these artworks is vital in validating ethically problematical applications of biotechnology for art. It is argued that the affective, visceral qualities of living artworks may spur the audience to adjust, revise or develop their personal ethical framework.

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              Transplantation of chondrocytes utilizing a polymer-cell construct to produce tissue-engineered cartilage in the shape of a human ear.

              This study evaluates the feasibility of growing tissue-engineered cartilage in the shape of a human ear using chondrocytes seeded onto a synthetic biodegradable polymer fashioned in the shape of a 3-year-old child's auricle. A polymer template was formed in the shape of a human auricle using a nonwoven mesh of polyglycolic acid molded after being immersed in a 1% solution of polylactic acid. Each polyglycolic acid-polylactic acid template was seeded with chondrocytes isolated from bovine articular cartilage and then implanted into subcutaneous pockets on the dorsa of 10 athymic mice. The three-dimensional structure was well maintained after removal of an external stent that had been applied for 4 weeks. Specimens harvested 12 weeks after implantation and subjected to gross morphologic and histologic analysis demonstrated new cartilage formation. The overall geometry of the experimental specimens closely resembled the complex structure of the child's auricle. These findings demonstrate that polyglycolic acid-polylactic acid constructs can be fabricated in a very intricate configuration and seeded with chondrocytes to generate new cartilage that would be useful in plastic and reconstructive surgery.
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                Author and article information

                Contributors
                +4755582510 , nora.vaage@svt.uib.no
                Journal
                Nanoethics
                Nanoethics
                Nanoethics
                Springer Netherlands (Dordrecht )
                1871-4757
                1871-4765
                3 March 2016
                3 March 2016
                2016
                : 10
                : 87-104
                Affiliations
                Centre for the Study of the Sciences and the Humanities (SVT), University of Bergen, Allégaten 34, Pb 7805, 5020 Bergen, Norway
                Article
                253
                10.1007/s11569-016-0253-6
                4791467
                27069514
                33accd0b-d409-4744-b2bb-5fe4a1a2acfb
                © The Author(s) 2016

                Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

                History
                : 3 December 2015
                : 5 February 2016
                Funding
                Funded by: FundRef http://dx.doi.org/http://dx.doi.org/10.13039/501100005036, Universitetet i Bergen;
                Categories
                Original Paper
                Custom metadata
                © Springer Science+Business Media Dordrecht 2016

                Ethics
                bioethics,art and morality,bioart,validation,tissue culture and art project
                Ethics
                bioethics, art and morality, bioart, validation, tissue culture and art project

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