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Tumor location and IDH1 mutation may predict intraoperative seizures during awake craniotomy.
Tal Gonen
1 ,
Rachel Grossman ,
Razi Sitt ,
Erez Nossek ,
Raneen Yanaki ,
Emanuela Cagnano ,
Akiva Korn ,
Daniel Hayat ,
Zvi Ram
Nov 2014
2-HG = 2-hydroxyglutarate,
AED = antiepileptic drug,
HGG = high-grade glioma,
KPS = Karnofsky Performance Scale,
LGG = low-grade glioma,
LOS = length of hospital stay,
SMA = supplementary motor area,
awake craniotomy,
brain tumors,
isocitrate dehydrogenase 1 mutation,
oncology,
seizures,
supplementary motor area
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Abstract
Intraoperative seizures during awake craniotomy may interfere with patients' ability to cooperate throughout the procedure, and it may affect their outcome. The authors have assessed the occurrence of intraoperative seizures during awake craniotomy in regard to tumor location and the isocitrate dehydrogenase 1 (IDH1) status of the tumor.
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Author and article information
seizures,2-HG = 2-hydroxyglutarate,AED = antiepileptic drug,HGG = high-grade glioma,KPS = Karnofsky Performance Scale,LGG = low-grade glioma,LOS = length of hospital stay,SMA = supplementary motor area,awake craniotomy,brain tumors,isocitrate dehydrogenase 1 mutation,oncology,supplementary motor area
seizures, 2-HG = 2-hydroxyglutarate, AED = antiepileptic drug, HGG = high-grade glioma, KPS = Karnofsky Performance Scale, LGG = low-grade glioma, LOS = length of hospital stay, SMA = supplementary motor area, awake craniotomy, brain tumors, isocitrate dehydrogenase 1 mutation, oncology, supplementary motor area