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Abstract

Here we review the history, clinical significance, pathology and molecular pathogenesis of Citrobacter rodentium, the causative agent of transmissible murine colonic hyperplasia. C. rodentium serves as an important model pathogen for investigating the mechanisms controlling attaching and effacing pathology, epithelial hyperproliferation, and tumor promotion in the distal colon of the mouse.

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PubMed ID:: 11334751

DOI:: 10.1016/S1286-4579(01)01387-9

ScienceOpen disciplines: Chemistry

Keywords: Animals,Bacterial Proteins,genetics,metabolism,Citrobacter freundii,pathogenicity,Cocarcinogenesis,Colon,microbiology,pathology,Colonic Diseases,Colonic Neoplasms,etiology,Disease Models, Animal,Enterobacteriaceae Infections,Humans,Hyperplasia,Mice,Virulence

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ScienceOpen disciplines: Chemistry

Keywords: Animals, Bacterial Proteins, genetics, metabolism, Citrobacter freundii, pathogenicity, Cocarcinogenesis, Colon, microbiology, pathology, Colonic Diseases, Colonic Neoplasms, etiology, Disease Models, Animal, Enterobacteriaceae Infections, Humans, Hyperplasia, Mice, Virulence

Molecular pathogenesis of Citrobacter rodentium and transmissible murine colonic hyperplasia.

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Microbiology Independent Research Journal (MIR Journal)

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