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      Takotsubo syndrome: between evidence, myths, and misunderstandings Translated title: Takotsubo-Syndrom: Evidenz, Mythen, Missverständnisse

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          Abstract

          Takotsubo syndrome (TS) is an acute cardiac condition characterized by transient wall motion abnormalities mostly of the left ventricle. First described in 1990, TS has gained substantial attention during the past 15 years. However, the disease is still underdiagnosed. Prospective studies on TS are largely lacking, and the condition remains incompletely understood. In addition, significant misconceptions and misunderstandings are evident, contributing to potentially severe underestimation. Here, we review important aspects of TS with a focus on pitfalls, misinterpretations, and knowledge gaps considered important during diagnosis and management of the disease.

          Electronic supplementary material

          The online version of this article (10.1007/s00059-020-04906-2) contains the references to the tables. The article and additional material are available in the electronic full text archive at http://www.springermedizin.de/herz. You will find the additional material at the end of the article under “Supplementary Material”.

          Translated abstract

          Das Takotsubo-Syndrom ist eine akute Erkrankung, die durch transiente Wandbewegungsstörungen überwiegend der linken Herzkammer gekennzeichnet ist. Nachdem sie 1990 erstmals beschrieben wurde, hat sie insbesondere in den letzten 15 Jahren enorme Aufmerksamkeit erfahren. Dennoch ist die Erkrankung unterdiagnostiziert. Es gibt kaum prospektive Studien, und das Takotsubo-Syndrom ist in vielen Aspekten noch nicht ausreichend verstanden. Darüber hinaus existieren zahlreiche Missverständnisse, die potenziell dazu beitragen, die Erkrankung zu unterschätzen. Hier geben die Autoren einen Überblick über wichtige Aspekte des Takotsubo-Syndroms unter besonderer Berücksichtigung möglicher Fehlinterpretationen und Wissenslücken, die für Diagnose und Behandlung von Bedeutung sind.

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          Natural history and expansive clinical profile of stress (tako-tsubo) cardiomyopathy.

          This study was designed to define more completely the clinical spectrum and consequences of stress cardiomyopathy (SC) beyond the acute event. Stress cardiomyopathy is a recently recognized condition characterized by transient cardiac dysfunction with ventricular ballooning. Clinical profile and outcome were prospectively assessed in 136 consecutive SC patients. Patients were predominantly women (n = 130; 96%), but 6 were men (4%). Ages were 32 to 94 years (mean age 68 +/- 13 years); 13 (10%) were 2 months in 5%. Right and/or left ventricular thrombi were identified in 5 patients (predominantly by CMR imaging), including 2 with embolic events. Three patients (2%) died in-hospital and 116 (85%) have survived, including 5% with nonfatal recurrent SC events. All-cause mortality during follow-up exceeded a matched general population (p = 0.016) with most deaths occurring in the first year. In this large SC cohort, the clinical spectrum was heterogeneous with about one-third either male,
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            SCAI clinical expert consensus statement on the classification of cardiogenic shock

            The outcome of cardiogenic shock complicating myocardial infarction has not appreciably changed in the last 30 years despite the development of various percutaneous mechanical circulatory support options. It is clear that there are varying degrees of cardiogenic shock but there is no robust classification scheme to categorize this disease state.
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              Cardiogenic Shock Classification to Predict Mortality in the Cardiac Intensive Care Unit

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                Author and article information

                Contributors
                napp.christian@mh-hannover.de
                Journal
                Herz
                Herz
                Herz
                Springer Medizin (Heidelberg )
                0340-9937
                1615-6692
                23 March 2020
                23 March 2020
                2020
                : 45
                : 3
                : 252-266
                Affiliations
                GRID grid.10423.34, ISNI 0000 0000 9529 9877, Department of Cardiology and Angiology, , Hannover Medical School, ; Carl-Neuberg-Str. 1, 30625 Hannover, Germany
                Article
                4906
                10.1007/s00059-020-04906-2
                7198647
                32206851
                39b73ae1-4c07-45f1-9947-45f477f810f3
                © The Author(s) 2020

                Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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                © Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2020

                stress cardiomyopathy,acute heart failure,cardiogenic shock,mechanical circulatory support,pulmonary artery catheterization,stresskardiomyopathie,akute herzinsuffizienz,kardiogener schock,mechanische kreislaufunterstützung,pulmonalarterienkatheter

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